thyroid hormone Flashcards

1
Q

hypothalamus produces

A

Thyrotropin-releasing hormones

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2
Q

pituitary secretes

A

Thyroid Stimulating Hormone

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3
Q

Thyroid gland produces

A

Thyroxine

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4
Q

largest endocrine gland

A

thyroid hormone

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5
Q

calcitonin is secreted by____ cells

A

parafollicular C cells

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6
Q

calcitonin inhibits _____ and prmotes ______

A

ihibits bone resoprtion, promotes bone formation

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7
Q

calcitonin is secreted when _____ rises

A

blood calcium

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8
Q

Thyroid hormone functions

A

regulate body metabolism, neurologic development, tissue growth, sexual maturation

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9
Q

colloid is rich in ______ and is main storage site of ______

A

thyroglobulin, thyroid hormones

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10
Q

formation of thyroid hormones

A
  1. follicular cell synthesizes enzymes and thyroglobulin
  2. 1-is co-transported into cell with Na+
  3. Enzyme (TPO) adds iodine to thyroglobulin making MIT/DIT residues to form T3 and T4
  4. When stimulated by TSH, thyroglobulin is taken back into cell
  5. Enzymes separate T3 and T4 from protein
  6. Free T3/T4 enter circulation
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11
Q

amino acid derived hormone from tyrosine

A

T4 aka Thyroxine

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12
Q

T4 is a precursor to

A

T3

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13
Q

T4 reference range

A

Males: 4.6-10.5 ug/dL
Females: 5.5-11.0 ug/dL

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14
Q

Most active thyroid hormone

A

T3

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15
Q

T3 is affected by variations in _____

A

thyroxine binding globulin (TBG)

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