thyroid drugs Flashcards
replacement hormone for the treatment of hypothyroidism
levothyroxine
emergency treatment if myxedema coma (IV induced)
levothyroxine
major adverse effect of levothyroxine?
overmedication can result in indications of hyperthyroidism ( anxiety, tachycardia, palpatations, altered appetite, abdomincal cramping, heat intolerance, fever, diaphoresis, weight loss, menstrual irregularities)
when should you take levothyroxine?
take on an empty stomach (before breakfast daily)
- seperate your medication and levo by about 3 hrs. especially binding agents (antacids, cholestyramine, iron and calcium supplements ) and sucralfate as these will reduce the effects of levo.
- levo can increase anticogulants effects by warfarin by breaking down vit k
what medication is it that the generics and brands are not interchangable.
levothyroxine
treatment for graves disease, produces a euthyroid state prior to thyroid removal surgery, as an adjunet to irradation of the thyroid gland & in the emergency treatment of thyroidtoxicosis.
propylthiouracil (PTU)
what do you give a patient with an overactive thyroid?
PTU
what is the administration of PTU?
- oral (begins within 30 mins)
- administer medication at consistent times each ay and with meals to maintain a consistent therapuetic levels and decreases gastric distress
- advise the patient thhat theurpuetic effects may take 1-2 weeks to be evident
what is the adverse effects of PTU?
- overmedication can result in indications of hypothyroidism
- **agranulocytosis
- liver injury, hepatitis
while taking PTU, you should monitor for signs of ____ indicating inadequate dosing
hyperthyroidism
how is radioactive iodine administered?
orally
what are some important things you should tell patient when taking radioactive iodine?
- patient should void frequently to avoid irradition of gonads
- limit contact with patient to 30 min/day/person for 2-5 ays.
- avoid in pregnancy (avoid becoming pregnant for 6mo to 1 yr after treatment)
what is given for thyroid intoxication or surgery?
lugols solution
is lugols solution radioactive?
no!
what are the adverse effect you should closely monitor for with lugols solution?
- iodism due to corrosive property (metallic taste, stomatitis, sore teeth and gums, frontal HA, skin rash)
- iodism (early toxicity) may progress to overdose (severe GI distress and swelling of the glottis.)
how do you know the lugols solutions has worked?
weight gain, vital signs within expected limits, **decreased t4 levels, reduction in size of thyroid gland, patient will get adequate sleep, achieve and maintain appropriate weight, maintain BP and HR within expected reference range, and to be free of complication of hyperthyroidism.
what should you do to maintain a theupuetic response with lugols solutions?
take at same time everyday
a nurse is caring for a client who is taking PTU , for which of the following adverse effects of the medication should the nurse monitor?
a. bradycardia
b. insomnia
c. heat intolerance
d. weight loss
A. bradycardia
a nurse is caring for an older adult client in a long-term care facility who has hypothyroidism and is beginning levothyroxine. which of the following dosage should the nurse expect for this client?
a. the client will start high dose, and the dose will be tapered down as needed.
b. the client will remain on the initial dosage during the course of treatment
c. the client dosage will be adjusted daily based on blood levels.
d. the client will start ona low dose, which will be gradually increased.
d. the client will start ona low dose, which will be gradually increased.
all questions on pg. 1223 in textbook
loookkk! may be on exam :]
