endocrine drugs

Question 1

Anterior pituitary hormone/growth hormones stimulate overall growth and the production of protein, and decauses the use of glucose.
what drug?

Answer 1

Somatropin

Question 2

Will adults with growth hormones deficiencies taking somtropin get taller?

Answer 2

no, they will just put on muscle mass

Question 3

what is the adverse effect that stands out while taking somtropin?

Answer 3

hyperglycemia (observe for polyphagia,polydipsia,polyuria)

also, hypercalciuria and renal calculi

Question 4

what shoud happen when the epiphyseal close?

Answer 4

stop the treatment

Question 5

what should a nurse monitor while patient is taking somotropin?

Answer 5

• periodic xrays of wrist

- obtains pts baseline height and weight, then measure monthly

Question 6

Avoid concurrent use of ____ and somatropin is possible.

Answer 6

glucocorticoids

can counteract growth-promoting effects.

Question 7

to treat both children and adults with excessive growth hormone (agromegaly and gigantism)

Answer 7

somatostatin

cause is because of lesions on the pituatary.

Question 8

what are the adverse effects that stand out with somatostatin?

Answer 8

GI problems; n/v, diarrhea, abdominal discomfort
development of gallstones
** elevated liver enzymes
hyper or hypo glycemia 
heart problems

Question 9

When should you administer somatostatin?

Answer 9

between meals or at bedtime to minimize adverse GI effects

Question 10

ADH replacement drug is?

Answer 10

desmopressin

Question 11

what is desmopressin used for?

Answer 11

they are used to treat diabetes insipidus

Question 12

what is the major adverse effect os desmopressin?

Answer 12

• too much water reabsorbtion (water intoxication) [sleepiness,confusion, pounding headache]
• excessive vasoconstriction [monitor ECG and BP]

Question 13

the big precautions for desmopressin is?

Answer 13

risk for gangrene in peripheral circulation [while giving IV, be mindful of this]

Question 14

the goal for patients taking desmopressin is?

Answer 14

the reduction of urine volume and to return to normal levels of urinary output.

Question 15

a nurse caring for a client who is prescribes somatropin to simulate growth. the nurse should plan to monitor the clients urine for which of the following?

a. bilirubin
b. protein
c. potassium
d. calcium

Answer 15

d.calcium

a large amount of calcium may be present in the urine of a client who takes somatropin. this puts client at risk for renal calculi

Question 16

a teaching plan for a parent who child is receiving somtropin should include what important information?

1. the patient must adhere to therapy to prevent mental retardation
2. the medication cannot be given orally; it can be given only parenterally
3. if growth hormone is begun is adolescent; it can add up to 6 in in height.
4. growth hormone therapy requires frequent blood work.

Answer 16

2. the medication cannot be given orally; it can be given only parenterally

Question 17

which of the following findings would the nurse considere to be effect of somatropin? select all that apply.

1. increase in the lenght and weight of long bones
2. organ,muscle, and connective tissue growth
3. increased synthesis of proteins
4. lowering the serum glucose levels
5. increase in fat deposits around the abdomen

Answer 17

1. increase in the lenght and weight of long bones
2. organ,muscle, and connective tissue growth
3. increased synthesis of proteins

Question 18

the client with neurogenic diabetes insipidus is being started on an oral dose of desmopressin. which instructions should the nurse include in the teaching plan?

1. use the drug only if urine output is excessive
2. use twice the prescribed dose if you miss a dose
3. obtain and record your weight each morning
4. use an nsaid such as ibuprofen if leg cramping occurs while walking.

Answer 18

3. obtain and record your weight each morning

Question 19

a client with metastatic colon cancer is experiencing bowel-related complications of the cancer and treatment somatostatin has been ordered. the nurse will anticipate which therapuetic effect from this drug?

1. decrease in the number of diarrheal stools per day.
2. slowing of the matestatic spead of the cancer.
3. increase in lean body mass and fat deposits.
4. episodes of hypo and hyperglycemia

Answer 19

1. decrease in the number of diarrheal stools per day.

Question 20

which of the following assessment finding would indicate that therapuetic goals have been achieved for a client with diabetes insipidus being treated with desmopressin?

1. decreasing signs of dehydration
2. increasing pulse and urine output
3. decreasing urine spefici gravity
4. decreasing hyperglycemia

Answer 20

1. decreasing signs of dehydration