rheumatoid arthritis

Question 1

what are the drugs we should know for rheumatoid arthritis and what do they do differently?

Answer 1

methotrexate (immunosuppressat med) non biologic
(cytotoxic agent) also used for cancer patient

etanercept (biologic ) (tumor necrosis factor anatogonist)

Question 2

what are some complications one could get with methotrexate?

Answer 2

infection
hepatic fibrosis
bone marrow suppresion
GI prob
fetal death/cogential abormalties

Question 3

should you take methotrexte while pregnant or trying to get pregnant?

Answer 3

NO

Question 4

what are some complications one could get with etanercept?

Answer 4

subcutaneous infection at injection site
iv fusion reaction
severe skin reaction (steven johnson syndrome)
heart failure
blood dycrasias

Question 5

which drug is contraindicated in client who have malignancies, active infection, hematologic disorder or during lactation?

Answer 5

ethnercept

Question 6

contraindicated in clients who have liver failure, alcoholism, and blood dyscrasias.

Answer 6

methotrexate

Question 7

which drug should you avoid live vaccines?

Answer 7

etnercept

Question 8

salicylates, other NSAIDS, sulfnamides, penicillin, and tetracyclines may cause toxicity in which drug?

Answer 8

methrotrexate

Question 9

a nurse is evaluating teaching a client who has rheumatoid arthritis and is beginning a prescription for methotrexate. which of the following statesments by the client indicate understandig of the teaching?

a. “ i will be sure to return to the clinic at the once a year to have my blood draw while im taking methotrexate.”
b. “I will take this medication on an empty stomach.”
c. “Ill let my doctor know if i develop sores in my mouth while taking this medication.”
d. “I should stop taking oral contraceptives while im taking methotrexate.”

Answer 9

c.”Ill let my doctor know if i develop sores in my mouth while taking this medication.”

Question 10

which drug should you NOT take with NSAIDS?

Answer 10

methrotrexate

-may cause severe and sometimes fetal myelosuppression

Question 11

the client will continue to take methrotrexate for treatmet of osteasarcoma. when teaching the client prior to discharge, which OTC drug must not be taken concurrently with methotrexate?

1. nonsteriodal anti-inflammatory drug pain relivers
2. antihistamines
3. laxtives
4. cough suppresants

Answer 11

1. nonsteriodal anti-inflammatory drug pain relivers

Question 12

the black box warning regarding possiblity of malignancy ad serious infection during therapy, including TB and bacterial sepsis.

Answer 12

etanercept