antiepileptic drugs

Question 1

if a patient is taking an AED and no history of seizure. why would they be taking it?

Answer 1

medication is also used for neuropathic pain

Question 2

can a patient go a week without their AED medication?

Answer 2

stopping this medication abrutly may cause withdrawal seizures. a refill is needed right away

Question 3

gingival hyperplasia, withdrawal symptoms, skin rash, and mild drowniess is the side effect for what drug>

Answer 3

hydantoins-phenytoin

Question 4

how should you administer hydantoins-phenytoin>

Answer 4

with food
inject iv form slowly
monitor vitals and plasma levels

Question 5

the contraindication for phenytoin is?

Answer 5

seizure caused by low blood sugar

Question 6

can you stop phenytoin suddenly?

Answer 6

NO

Question 7

you should never mix ___ with another drug. it will precipatate!!

Answer 7

hydantoins-phenytonin

Question 8

what does hydantoins-phenytonin interact wth?

Answer 8

dextrose solutions, cimetidine (any cytochrome c450 drugs), alcohol, oral contraceptives

Question 9

“stop the seizures before they start” with what drug?

Answer 9

carbamazepine (iminostillbenes)

Question 10

carbamazepine is sometimes given for people that have ___.

Answer 10

TMJ

Question 11

side effects for carbamazepine ?

Answer 11

*decreased excretion of water (fluid retention)
visual disturbances
skin rash
*bone marrow suppresion

Question 12

when giving carbamazepine, you should check to make sure the patient is not__.

Answer 12

asian. and if they are.. test for HLA-B 1502 gene, which can increase the risk of severe skin reactions

Question 13

what medication should you avoid grapefruit juice with?

Answer 13

carbmazepine
will increase plasma levels
–also with cause a false negative pregnancy test

Question 14

which medication treats all types of seizures?

Answer 14

valproic acid

Question 15

which medication treat grand mal seizure , the long ones

Answer 15

imunostillbenes-carbamazepine

Question 16

what else does valproic acid treat?

Answer 16

migraine headaches

Question 17

enhances the inhibitory effects of GABA
&
sodium and calcium channels are involved!

Answer 17

valproic acid

Question 18

liver toxicity and hyperammonia are side effects of?

Answer 18

valproic acid

ALSO more GI probs than the others

Question 19

women in childbearing age taking valproic acid should also take?

Answer 19

folic acid may help.

Question 20

a client is taking phenytoin, has noted symptoms of nystagmus,confusion,and ataxia. the nurse would suspect that the dose should be ?

Answer 20

reduced p.395 textbook

Question 21

carbamazepine has been prescribed for a 24 yr old client with control of partial seizures. the nurse will teach the client to immediately report:

1. blurred vision
2. leg cramps
3. blister-like rash
4. lethargy

Answer 21

3. blister-like rash