Thyroid Agonists Flashcards
1
Q
what are the 2 thyroid agonist drugs?
what are the other names for these drugs?
A
- T4: Levothyroxine
- T3: Liothyonine
2
Q
how is T4 administered?
A
orally
3
Q
which has a longer half life, T3 or T4?
A
T4 has a longer half life
4
Q
how long does administration of T4 take to have an effect?
A
6 days
5
Q
which is more potent, T3 or T4?
Which is faster acting, T3 or T4?
A
T3
T3
6
Q
when is T3 given orally only?
A
for immediate response in myxedema coma
7
Q
how to T3 and T4 work?
A
T4 is bound to thyroglobulin, it enters the cell and gets converted to T3, it enters the nucleus and binds to the receptor
8
Q
When is T4 given?
A
- Hashimoto’s Disease
- After thyroid removal surgery
9
Q
what is the effect of giving T3 or T4?
A
increase BMR
maintain body temperature
increase HR
Increase TPR
increase blood sugar
increase synthesis of FA
decrease plasma triglycerides
maintain normal physical and mental growth
