Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Basic Haemotology (1204) > Thymus And Lymph Node > Flashcards

Thymus And Lymph Node Flashcards

1
Q

Where is the Thymus located

A

Anterior Mediastinum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the main cell components in the thymus

A

T Lymphocytes, Epithelial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where are the epithelial cells located into the body

A

In the third pharyngeal pouch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

In the cortex are the epithelial cells dense or loose

A

Dense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

In the Medulla, are the epithelial cells loose or dense

A

Loose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the name given to the epithelial cells in the medulla

A

Hassall Corpuscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the main function of the thymus

A

Development of Self Tolerance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

List the types of Developmental diseases of the thymus

A

Agenisis and hypoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

List the type of Acquired diseases of the thymus

A

Atrophy, Hyperplasia, Neoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the names of the combined deficiencies in thymic developmental immunodeficiencies

A

Bone Marrow Failure
Severe Combined Immunodeficiency
T and B cell Deficiency
2 degree thymic agenesis/ hypoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the name of the cellular deficiencies in thymic developmental abnormalities

A

1st degree thymic ageneis/ hypoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

At what age is the thymic mass at its highest

A

Puberty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the normal thymic mass during Birth, Puberty, 25 years, 60 years, 70 years

A

15, 35, 25, <15, <5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What causes acquired thymic Atrophy

A

Age, malnutrition, stress, terminal illness, cytotoxic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The presence of lymphoid follicles is a characteristic of what disease

A

Thymic Hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the associated disease for Thymic Hyperplasia

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What areas in the body exhibits weakness due to Myasthenia Gravis

A

Proximal Girdle and Bulbar Weakness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

True or False, In Myasthenia Gravis, An increase in muscle use decrease the muscle’s ability to function

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

In thymic neoplasms, what disease has an epithelial origin

A

Thymomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

In thymic neoplasms, what disease has a lymphoid origin

A

Lymphomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are germ cell tumors due to thymic neoplasms called

A

Teratomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

True or False, the most common neoplasms of the thymus is of epithelial origin

A

True

23
Q

True or False, majority of thymomas are malignant

A

False, they are cytologically and biologically benign

24
Q

What type of Thymoma is cytologically benign but biologically aggressive

A

Type 1 (invasive thymoma)

25
Q

What type of Thymoma is rare

A

Type 2 - Thymic Carcinoma

26
Q

True or False, thymomas that are cytologically sand biologically malignant are rare

A

True

27
Q

What disease usually has an anterior mediastinal mass

A

Thymoma

28
Q

What is the average age group for patients with Thymoma

A

50 year old

29
Q

What percentage of patients with Thymomas are asymptomatic

A

10-50%

30
Q

What percentage of patients with Thymomas have pressure symptoms

A

10-30%

31
Q

What percentage of patients with Thymomas have systemic features

A

30-40%

32
Q

What disease is usually associated with Myasthenia Gravis (15-45%)

A

Thymoma

33
Q

What disease is associated with thymomas (21%)

A

Cytopenias

34
Q

What disease is associated with Thymoma (6%)

A

Acquired hypo gamma-globulinaemia

35
Q

What is the term given to a lymph node enlargement

A

Lymphadenopathy

36
Q

What 3 substances can cause Reactive Hyperplasia of the Lymph nodes

A

Microbes
Cell Debris
Foreign Material

37
Q

True or False, Reactive Hyperplasia is non-specific

A

True

38
Q

In reactive Hyperplasia, what cells process antigens

A

Macrophages

39
Q

In reactive Hyperplasia, what cell is activated by the lymph nodes

A

Resting/memory lymphocytes

40
Q

What morphological change occurs to the lymph nodes in reactive Hyperplasia

A

Size/cytoplasm
Pallor
Nucleoli and mitosis

41
Q

What does the the lymph node secrete in reactive Hyperplasia

A

Cytokines

42
Q

In reactive Hyperplasia, antigenic stimulation for < 8days, results in ____

A

Diffuse Hyperplasia (T cell)

43
Q

In reactive Hyperplasia, antigenic stimulation for > 15 days, results in ____

A

Follicular Hyperplasia (B cell)

44
Q

What lymphadenopathy is usually microbial with localized and direct drainage of infection

A

Acute Reactive Hyperplasia

45
Q

What are the localized direct drainage of infection

A

Tonsils
Inguinal
Enteric

46
Q

What are the generalized drainage of infection

A

Viral infections
Bacteraemia
Septicaemia

47
Q

True or False, acute reactive Hyperplasia is asymptomatic

A

False, it is painfully tender

48
Q

What is the gross display of lymph nodes in acute reactive Hyperplasia

A

Red-grey

Intact capsule - perinodal extension

49
Q

What is the microscopic display of lymph nodes in acute reactive Hyperplasia

A

Sinusoidal congestion
Polymorphs - necrosis
Follicular Hyperplasia

50
Q

What histologic appearance varies in reactive Hyperplasia

A

Age, immune capability, past exposure, inciting factor, duration

51
Q

A 1st degree lymphoma is referred to as ________

A

Leukemia

52
Q

In chronic reactive Hyperplasia, what cell is associated with an increase in antibody production

A

Follicular (B cell)

53
Q

In Chronic Reactive Hyperplasia, what cell is associated with viral infections and cytotoxicity

A

Paracortical/ diffuse (t cell)

54
Q

What cell is associated with cytokine effect in lymph nodes draining tumors

A

Sinus histocytosis

Basic Haemotology (1204) (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions