Thrombolysis Eligibility

Question 1

When is thrombolysis been proven to be very effective?

Answer 1

<3 hours of onset of symptoms in ischaemic stroke

- proven to decrease death and severe disability

Question 2

What are the 2 timelines that IV thrombolysis can be given on? (depending on centre)

Answer 2

<3 hours after onset of symptoms
OR
<6 hours after onset of symptoms

Question 3

What are the main contraindications to IV thrombolysis?

Answer 3

BP above 180/110 (high risk of haemorrhage)
Brain scan features suggesting haemorrhage
Low GCS

Question 4

What agent is given for thrombolysis in ischaemic stroke?

Answer 4

IV recombinant tissue plasminogen activator