Thrombocytosis Flashcards
Secondary thrombocytosis is also known as
Reactive
Primary thrombocytosis is also known as
Autonomous
Usually with bleeding and thrombotic complications
Primary Thrombocytosis (AUTONOMOUS)
<1,000 x 10^9/L
Secondary Thrombocytosis (REACTIVE)
> 1,000 x 10^9/L
Primary Thrombocytosis (AUTONOMOUS)
Defective platelet function
Primary Thrombocytosis (AUTONOMOUS)
Normal platelet function
Secondary Thrombocytosis (REACTIVE)
Essential thrombocytopenia (ET)
Primary Thrombocytosis (AUTONOMOUS)
Acute infection
Secondary Thrombocytosis (REACTIVE)
Solid organ malignancies
Secondary Thrombocytosis (REACTIVE)
Anemia (especially: iron deficiency, hemolysis,
hemorrhage)
Secondary Thrombocytosis (REACTIVE)
Myelodysplastic syndrome (MDS)
Primary Thrombocytosis (AUTONOMOUS)
Myelofibrosis
Primary Thrombocytosis (AUTONOMOUS)
Chronic myeloid leukemia
(CML)
Primary Thrombocytosis (AUTONOMOUS)
Chronic inflammatory disorders (e.g., autoimmune, TB, sarcoidosis)
Secondary Thrombocytosis (REACTIVE)