Therapeutic Pain Management Flashcards
what are the steps outlined by WHO for pain management?
Step 1: non-opioid with or without combo drug
Step 2: Opioids + non-opioid with or without combo drug
Step 3: Opioids with or without non-opioid with or without combo drug
what is standard dosing for APAP?
325-1000mg q4-6h PRN
what is the NTE recommendation when using APA as “round the clock” treatment for musculoskeletal pain?
what if they have liver damage, chronic alcohol use, or an older adult?
4g/day
2-3g/day
what is pediatric dosing for APAP?
10-15mg/kg q4-6h
Ketorolac COX selectivity?
COX 1
Ibuprofen and naproxen COX selectivity?
non-selective
Celecoxib COX selectivity?
COX 2
possible adverse effects of COX 1 inhibitors?
GI bleed
ulcers
possible adverse effects of COX 2 inhibitors?
cardiovascular complications/MI
possible adverse effects of all NSAIDs?
dyspepsia
renal injury
what drug-drug interactions known as “the triple whammy” increase the risk of acute kidney injury?
NSAID + ACEi/ARB + diuretic
Ketorolac should not be used longer than?
5 days
How can ketorolac be administrated?
PO,IM/IV/ and opthalmic
should ketorolac be renally adjusted?
yes
Typical dosing of ibuprofen?
what is dosing if used for osteoarthritis?
200-400mg q4-6h
400-800mg q4-6h