Therapeutic Pain Management Flashcards

1
Q

what are the steps outlined by WHO for pain management?

A

Step 1: non-opioid with or without combo drug
Step 2: Opioids + non-opioid with or without combo drug
Step 3: Opioids with or without non-opioid with or without combo drug

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2
Q

what is standard dosing for APAP?

A

325-1000mg q4-6h PRN

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3
Q

what is the NTE recommendation when using APA as “round the clock” treatment for musculoskeletal pain?
what if they have liver damage, chronic alcohol use, or an older adult?

A

4g/day
2-3g/day

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4
Q

what is pediatric dosing for APAP?

A

10-15mg/kg q4-6h

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5
Q

Ketorolac COX selectivity?

A

COX 1

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6
Q

Ibuprofen and naproxen COX selectivity?

A

non-selective

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7
Q

Celecoxib COX selectivity?

A

COX 2

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8
Q

possible adverse effects of COX 1 inhibitors?

A

GI bleed
ulcers

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9
Q

possible adverse effects of COX 2 inhibitors?

A

cardiovascular complications/MI

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10
Q

possible adverse effects of all NSAIDs?

A

dyspepsia
renal injury

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11
Q

what drug-drug interactions known as “the triple whammy” increase the risk of acute kidney injury?

A

NSAID + ACEi/ARB + diuretic

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12
Q

Ketorolac should not be used longer than?

A

5 days

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13
Q

How can ketorolac be administrated?

A

PO,IM/IV/ and opthalmic

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14
Q

should ketorolac be renally adjusted?

A

yes

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15
Q

Typical dosing of ibuprofen?
what is dosing if used for osteoarthritis?

A

200-400mg q4-6h
400-800mg q4-6h

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16
Q

Typical dosing of naproxen?

A

500-1000mg

17
Q

how long does it take for pain relief from diclofenac?
it should only be used for up to _ peripheral areas on the body

A

up to 7 days
2

18
Q

what are the clinical presentations of osetoarthritis?

A

asymmetrical
hands, hips, knee, spine, feet
bony proliferations
pain resolves with movement, worsens at rest

19
Q

what is first line treatment for osteoarthritis?
alternatives?

A

APAP
NSAIDs, capsaicin

20
Q

duloxetine can be used to treat what pain site with osteoarthritis?

A

the knee