The tissue level of organization- Connective tissue Flashcards

1
Q

What are the components of connective tissue

A
  1. Specialized cells
  2. Extracellular protein fibers
  3. Fluid called ground substance
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2
Q

What are the functions of connective tissues?

A

– Establishing a structural framework for the body
– Transporting fluids and dissolved materials
– Protecting delicate organs
– Supporting, surrounding, and interconnecting other types of tissue
– Storing energy reserves, especially triglycerides
– Defending the body from invading microorganisms

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3
Q

State the categories of connective tissues

A
  1. Connective tissue proper
    * Connect and protect
  2. Fluid connective tissues
    * Transport
  3. Supporting connective tissues
    * Structural strength
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4
Q

State the categories of connective tissue proper

A

– Loose connective tissue
* More ground substance, fewer fibers
* Example: fat (adipose tissue)
– Dense connective tissue
* More fibers, less ground substance
* Example: tendons

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5
Q

What are the cells of connective tissue proper

A

– Fibroblasts
– Fibrocytes
– Adipocytes
– Mesenchymal cells
– Melanocytes
– Macrophages
– Mast cells
– Lymphocytes
– Microphages

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6
Q

Describe Fibroblasts

A

– The most abundant cell type
– Found in all types of connective tissue proper
– Secrete proteins and hyaluronan (cellular ceme

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7
Q

Describe Fibrocytes

A

– Second most abundant cell type
– Maintain connective tissue fibers

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8
Q

Describe Adipocytes

A

– Fat cells
– Each cell stores a single, large fat droplet

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9
Q

Describe Mesenchymal cells

A

– Stem cells that respond to injury or infection
– Differentiate into fibroblasts, macrophages, etc.

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10
Q

Describe Melanocytes

A

– Synthesize and store the brown pigment melanin

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11
Q

Describe Macrophages

A

– Large phagocytic cells of the immune system
– Engulf pathogens and damaged cells
– Fixed macrophages stay in tissue
– Free macrophages migrate

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12
Q

Describe Mast Cells

A

– Stimulate inflammation after injury or infection
* Release histamine and heparin
– Basophils are leukocytes that also contain histamine and heparin

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13
Q

Describe lymphocytes

A

– Migrate throughout the body
– May develop into plasma cells, which produce
antibodies

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14
Q

Describe Microphages

A

– Phagocytic blood cells (neutrophils, eosinophils)
– Attracted to signals from macrophages and mast cells

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15
Q

State the three types of connective tissue fibers

A
  1. Collagen fibers
  2. Reticular fibers
  3. Elastic fibers
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16
Q

Describe Reticular fiber

A

– Form a network of interwoven fibers (stroma)
– Strong and flexible
– Resist forces in many directions
– Stabilize functional cells (parenchyma) and structures
– Example: sheaths around organs

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17
Q

Describe Elastin Fibers

A

– Contain elastin
– Branched and wavy
– Return to original length after stretching
– Example: elastic ligaments of vertebrae

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18
Q

What is Ground substance

A

– Is clear, colorless, and viscous
– Fills spaces between cells and slows pathogen
movement

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19
Q

Describe Loose connective tissues

A

– “Packing materials”
– Fill spaces between organs, cushion cells, and support
epithelia

20
Q

Describe embryonic connective tissues

A

– Not found in adults
– Mesenchyme (embryonic connective tissue)
* First connective tissue in embryos
– Mucous connective tissue
* Loose embryonic connective tissue

21
Q

What are the types of loose connective tissues in adults

A
  1. Areolar tissue
  2. Adipose tissue
  3. Reticular tissue
22
Q

Describe the Areolar Tissue

A

– Least specialized
– Open framework
– Viscous ground substance
– Elastic fibers
– Holds capillary beds
* Example: under skin (subcutaneous layer)

23
Q

Describe Adipose Tissue

A

– Contains many adipocytes (fat cells)
* Adipocytes in adults do not divide
– Expand to store fat
– Shrink as fats are released
* Mesenchymal cells divide and differentiate
– To produce more fat cells
– When more storage is needed
– May be removed (temporarily) via liposuction in cosmetic surgery

24
Q

What is white fat?

A

– Most common
– Stores fat and absorbs shocks
– Slows heat loss (insulation)

25
What is Brown Fat
– Found in babies and young children – More vascularized – Adipocytes have many mitochondria – Breakdown of lipids releases energy and warms body
26
Describe the reticular tissue
Provides support – Reticular fibers form a complex, three-dimensional stroma – Support functional cells of organs – Found in liver, kidney, spleen, lymph nodes, and bone marrow
27
What is another name for dense connective tissue
Collagenous tissues
28
What are the three types of dense connective tissue
Dense regular * Dense irregular * Elastic
29
Describe Dense regular connective tissue
– Tightly packed, parallel collagen fibers * Tendons attach muscles to bones * Ligaments connect one bone to another and stabilize organs * Aponeuroses are tendinous sheets that attach a broad, flat muscle to another structure
30
Describe Dense irregular connective tissue
– Interwoven network of collagen fibers * Provides strength to dermis * Forms sheath around cartilages (perichondrium) and bones (periosteum) * Forms capsules around some organs (e.g., liver, kidneys, and spleen)
31
What are three layers of fasciae
1. Superficial fascia * Separates skin from underlying tissues 2. Deep fascia * Sheets of dense regular connective tissue 3. Subserous fascia * Lies between deep fascia and serous membranes that line body cavities
32
Fluid connective tissue include:
blood and lymph
33
Describe the blood
Contains a watery matrix called plasma – Contains cells and cell fragments, collectively known as formed elements * Red blood cells (erythrocytes) * White blood cells (leukocytes) * Platelets
34
Describe lymph
– Forms as interstitial fluid that enters lymphatic vessels – Monitored by immune system – Returned to veins near the heart
35
Supporting connective tissue include
cartilage and bone
36
What are the types of cartilage and describe
▪ Hyaline cartilage – Most common type – Tough and somewhat flexible – Reduces friction between bones – Found in synovial joints, rib tips, sternum, and trachea ▪ Elastic cartilage – Supportive but bends easily – Found in external ear and epiglottis Fibrocartilage – Very durable and tough – Limits movement – Prevents bone-to-bone contact – Found around joints, between pubic bones, and between spinal vertebrae
37
The types of cartilage growth are
– Interstitial growth * Enlarges cartilage from within – Appositional growth * Growth at outer surface of cartilage
38
Describe the bone
For weight support – Calcified (made rigid by calcium salts) – Resists shattering (flexible collagen fibers) – Osteocytes (bone cells) lie in lacunae * Arranged around central canals within matrix * Small channels through matrix (canaliculi) allow for exchange of materials with blood – Periosteum covers bone * Fibrous (outer) and cellular (inner) layers
39
What is the function of tissue membrane
– Physical barriers – Line or cover body surfaces – Consist of an epithelium supported by connective tissue
40
What are the four types of tissue membranes
1. Mucous membranes 2. Serous membranes 3. Cutaneous membrane 4. Synovial membranes
41
Describe the mucous membranes?
– Line passageways that have external connections – In digestive, respiratory, urinary, and reproductive tracts – Epithelial surfaces must be moist * To reduce friction * To facilitate absorption or secretion – Lamina propria is areolar tissue in mucous membranes
42
Describe the Serous membranes
– Line cavities that do not open to the outside – Thin but strong – Parietal portion lines inner surface of cavity – Visceral portion (serosa) covers the organs – Serous fluid reduces friction
43
What are the different types of serous membranes and describe
1. Peritoneum * Lines peritoneal cavity * Covers abdominal organs 2. Pleura * Lines pleural cavities * Covers lungs 3. Pericardium * Lines pericardial cavity * Covers heart
44
Describe the cutaneous membrane
– Skin that covers the body – Thick, relatively waterproof, and usually dry
45
Describe the synovial membranes
– Line synovial joint cavities – Movement stimulates production of synovial fluid for lubrication – Lack a true epithelium