The tissue level of organization- Connective tissue Flashcards
What are the components of connective tissue
- Specialized cells
- Extracellular protein fibers
- Fluid called ground substance
What are the functions of connective tissues?
– Establishing a structural framework for the body
– Transporting fluids and dissolved materials
– Protecting delicate organs
– Supporting, surrounding, and interconnecting other types of tissue
– Storing energy reserves, especially triglycerides
– Defending the body from invading microorganisms
State the categories of connective tissues
- Connective tissue proper
* Connect and protect - Fluid connective tissues
* Transport - Supporting connective tissues
* Structural strength
State the categories of connective tissue proper
– Loose connective tissue
* More ground substance, fewer fibers
* Example: fat (adipose tissue)
– Dense connective tissue
* More fibers, less ground substance
* Example: tendons
What are the cells of connective tissue proper
– Fibroblasts
– Fibrocytes
– Adipocytes
– Mesenchymal cells
– Melanocytes
– Macrophages
– Mast cells
– Lymphocytes
– Microphages
Describe Fibroblasts
– The most abundant cell type
– Found in all types of connective tissue proper
– Secrete proteins and hyaluronan (cellular ceme
Describe Fibrocytes
– Second most abundant cell type
– Maintain connective tissue fibers
Describe Adipocytes
– Fat cells
– Each cell stores a single, large fat droplet
Describe Mesenchymal cells
– Stem cells that respond to injury or infection
– Differentiate into fibroblasts, macrophages, etc.
Describe Melanocytes
– Synthesize and store the brown pigment melanin
Describe Macrophages
– Large phagocytic cells of the immune system
– Engulf pathogens and damaged cells
– Fixed macrophages stay in tissue
– Free macrophages migrate
Describe Mast Cells
– Stimulate inflammation after injury or infection
* Release histamine and heparin
– Basophils are leukocytes that also contain histamine and heparin
Describe lymphocytes
– Migrate throughout the body
– May develop into plasma cells, which produce
antibodies
Describe Microphages
– Phagocytic blood cells (neutrophils, eosinophils)
– Attracted to signals from macrophages and mast cells
State the three types of connective tissue fibers
- Collagen fibers
- Reticular fibers
- Elastic fibers
Describe Reticular fiber
– Form a network of interwoven fibers (stroma)
– Strong and flexible
– Resist forces in many directions
– Stabilize functional cells (parenchyma) and structures
– Example: sheaths around organs
Describe Elastin Fibers
– Contain elastin
– Branched and wavy
– Return to original length after stretching
– Example: elastic ligaments of vertebrae
What is Ground substance
– Is clear, colorless, and viscous
– Fills spaces between cells and slows pathogen
movement
Describe Loose connective tissues
– “Packing materials”
– Fill spaces between organs, cushion cells, and support
epithelia
Describe embryonic connective tissues
– Not found in adults
– Mesenchyme (embryonic connective tissue)
* First connective tissue in embryos
– Mucous connective tissue
* Loose embryonic connective tissue
What are the types of loose connective tissues in adults
- Areolar tissue
- Adipose tissue
- Reticular tissue
Describe the Areolar Tissue
– Least specialized
– Open framework
– Viscous ground substance
– Elastic fibers
– Holds capillary beds
* Example: under skin (subcutaneous layer)
Describe Adipose Tissue
– Contains many adipocytes (fat cells)
* Adipocytes in adults do not divide
– Expand to store fat
– Shrink as fats are released
* Mesenchymal cells divide and differentiate
– To produce more fat cells
– When more storage is needed
– May be removed (temporarily) via liposuction in cosmetic surgery
What is white fat?
– Most common
– Stores fat and absorbs shocks
– Slows heat loss (insulation)