the resting membrane potential Flashcards
Resting membrane potential of cardiac muscle
-80
Resting membrane potential of neurons
-70
Resting membrane potential skeletal muscles
-90
Resting membrane potential of smooth muscles
-50
Membrane potential
Electrical potential voltage difference across the plasma membrane
How do you measure the membrane potential
volt metre the micro electrode is a fine glass pipette the tip diameter is 1 µm cell penetrate cell membrane filled with the conducting solution
Resting potential
Membrane potential is the electrical charge access across the membrane and is always expressed as the potential inside the cell relative to the extracellular solution
Selected permeability of the cell membrane due to
Phospholipid bilayer
specific ion channels
Ion channel properties
Selective
gated: the pore can be open or change by conformational change in the protein
rapid ion flow: boys down the electrochemical gradient
How does the resting membrane potential arise
Membrane selected payable to potassium
When the chemical gradient for potassium and the electrical gradient for potassium are equilibrium there will be no net movement of potassium but there will be a negative membrane potential
How to calculate the equilibrium potential
The nerst to equation