Autonomic nervous system Flashcards

1
Q

Three divisions of the autonomic nervous system

A

Sympathetic
parasympathetic
enteric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the five divisions of the spinal column

A
Medullary
cranial
thoracic
Lumbar
sacral
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe the relative lengths and minor nations of the two neurons in the parasympathetic system

A

Long myelinated pre-ganglion

short unmyelinated post ganglion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

In parasympathetic system first gangly and is found where

A

Within the innervated tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Parasympathetic Anglian one ganglion to what type of receptors

A

Ganglion one as a cholinergic
acetyl-choline binds to the nicotinic acetyl choline receptor

Ganglion to is cholinergic
acetyl-choline binds to the muscarinic acetyl choline receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Muscarinic ACh receptor is what kind of receptor

A

G-protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

M2 receptor leads to of the parasympathetic nervous system

A

Bradycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Explain the relative lengths of the pre-and post embryonic neurons in the sympathetic nervous system

A

Short myelinated

alone unmyelinated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What kind of receptors are involved in the sympathetic nervous system

A

Androgenic receptors

alpha-1 alpha-2 beta one beta two

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

First ganglion of the parasympathetic system is what kind of receptor

A

Cholinergic, acetylcholine binds to nicotinic acetyl choline receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Post ganglia nerve is what kind of receptor

A

Binds noradrenaline to Katrina receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Post ganglia nerve is what kind of receptor symapthetic

A

Binds noradrenaline to adreno receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Explain sweat gland

A

Sweat gland sympathetic
instead of having typical noradrenaline binding to adreno receptor
have acetal choline binding to muscarinic ACh receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Adrenal glands

A

Nerve initiates in the Chromaffin cells
stimulates and ACh nicotinic receptor
which then releases the hormone adrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How can we follow logically intervene with the automatic nervous system activity

A
Degradation of transmitter
interaction with postsynaptic receptors
inactivation of transmitter
reuptake of transmitter
interaction with presynaptic receptor
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

ACh synthesis requires what enzyme

A

Choline acetyl transferase CAT

17
Q

Ach degradation requires were enzyme

A

acetyl choline esterase

18
Q

Nicotinic ACh receptors at the automatic ganglia and the neuromuscular junction different structure this can be useful

A

See activity of drug design

19
Q

Specific drug used to target the muscarinic Ach antagonist is

A

Tolteradine-useful overactive bladder

20
Q

Issues with devising drugs automatic nervous system

A

Relative lack of selectivity of cholinergic drugs means unwanted side effects

21
Q

Sludge is caused by massive discharge of the parasympathetic nervous system what could cause this

A

Drug overdose
Magic mushrooms
organophosphorus insecticides- Caerphilly modified is acetly cholineester

22
Q

Sludge

A

Saliva

lacrimation urination desiccation GI upset emesis

23
Q

mAch Agnes example

A

Bethanechol used to stimulate bladder emptying

24
Q

post ganglionic sympathetic neurons posses highly branched axonal network called

A

varicosities

25
Q

Neuro adrenaline vesical release requires

A

Calcium

26
Q

precursoers of noradenralin

A

tyrosine
DOPA
dompamine
noradenaline

27
Q

termination of noradenaline

A

uptake 1 on pre synapic membrane

uptake 2 on post synapic membrane

28
Q

NA which is to put into vesicales in the synapic membrane what happeens to

A

two enzymes act on COMT MAO

29
Q

agonist of B2 receptors

A

salbutamol used in asthma for bronchoconstricion