The pituitary gland (clinical case and discussion) Flashcards
What does hyper-secretion of growth hormone cause
Acromegaly (gigantism)
What does hyper secretion of ACTH
Cushing’s disease
What does hyper secretion of prolactin cause
Hyperprolactinaemia
What are the clinical features of Acromegaly
Spade like hands
wide feet
thick lips and tongue
carpal tunnel syndrome
sweating
What are complications of acromegaly
headache
chiasmal compression
diabetes mellitus
hypertension
What is a common cause of acromegaly
Hypersecretion of growth hormone caused by tumour
What does cushings syndrome cause
Excess corticosteroids
Therefore more tissue breakdown, sodium retention and insulin antagonism
What are the high value signs and symptoms in cushings syndrome
Skin atrophy
myoptathy
osteoporosis
What are intermeddiate value diagnostic symptoms in cushings syndrome
Pink striae
Facial mooning and hirsutism
Oedema
What are non specific symptoms or signs that are in cushings syndrome
Central obesity and hypertension
What is proximal myopathy
Generalised muscle weakness affecting the upper and/or lower limbs
What are the clinical manifestations of hyperprolactinameia in women
Galactorrhea - milk production
Infertility and menstrual cycle that is not regular
What are the clinical manifestations of hyperprolactinaemia in women
Galactorrhoea
Impotence - cant get a an erection
Headache
What are the physiological causes of hyperprolactinaemia
pregnancy, lactation and stress
What are the pharmacological causes of hyperprolactinaemia
Dopamine agonist antagonistic drugs
