The Heart Flashcards

1
Q

Where is the heart located?

A

The heart is located in the mediastinum and the base lies on the 5th rib.

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2
Q

What is the function of the heart?

A

The heart is basically a pump: it receives deoxygenated (more CO2) blood, sends it to the lungs to be exchanged with oxygenated blood and then pump it to the rest of the body.

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3
Q

What encloses and holds the heart in place?

A

The pericardium

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4
Q

What is another way to describe the inner layer of the pericardium?

A

The serous pericardium (has 2 layers)

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5
Q

What are the two layers of the serous pericardium?

A

The parietal (outer) and visceral (inner) layer

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6
Q

What is the space between the visceral and parietal layers of the serous pericardium called?

A

The pericardial space/cavity (fluid-filled)

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7
Q

What is the role of the coronary arteries?

A

Supplies O2 + nutrients to the muscles of the heart (myocardium)

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8
Q

The coronary arteries branch from the…

A

Ascending aorta

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9
Q

Which artery supplies the left ventricle?

A

The left main coronary artery supplies the left ventricle.

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10
Q

What does the left main coronary artery branch into? (3)

A
  1. It goes around the back of the heart into the left circumflex artery
  2. Then there’s the anterior interventricular artery (lies in the interventricular sulcus — separates the ventricles)
  3. Comes down and becomes the left anterior descending artery (LAD)
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11
Q

What does the right coronary artery branch into? (2)

A
  1. The right marginal artery (hint: marginal = side)
  2. Then the inferior interventricular artery (posterior)
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12
Q

What is the role of the coronary veins?

A

Picks up CO2 and waste from the heart

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13
Q

Where do the branches of the coronary veins converge?

A
  • The coronary sinus (think of it like rivers dumping water into a lake)
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14
Q

Is the coronary sinus at the posterior or anterior of the heart?

A

The posterior of the heart

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15
Q

Where does the coronary sinus dump its waste?

A

The right atrium

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16
Q

What vein dumps CO2 and waste into the coronary sinus?

A

The great cardiac vein (LEFT)

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17
Q

What are the coronary veins on the anterior of the heart? (4)

A

The great cardiac vein (LT) ; the small cardiac vein (RT); the anterior cardiac vein; and the oblique vein of the left atrium.

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18
Q

What are the coronary veins on the posterior of the heart? (3)

A

The coronary sinus (in the coronary sulcus); the middle cardiac vein; and the posterior vein of the left ventricle.

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19
Q

What are the branches of the left side of the thoracic aorta? (2)

A

The left subclavian artery and the left common carotid artery (CCA)

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20
Q

Does the right branches of the thoracic aorta come directly from the aorta?

A

No, they come from the brachiocepahalic artery

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21
Q

What are the branches of the brachiocephalic artery? (right branches of the thoracic aorta) (2)

A

The right common carotid and the right subclavian artery

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22
Q

What are the branches of the superior vena cava?

A

The left and right innominate veins (each has their own LT/RT subclavian and internal jugular vein)

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23
Q

What are the heart’s layers in its wall?

A

The epicardium, myocardium, and the endocardium

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24
Q

What is the endocardium’s location?

A

The most inner layer

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25
Q

What is the myocardium’s location?

A

The middle layer of the heart’s wall

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26
Q

The myocardium is the major structure for… (2)

A

Electrical conductivity and contraction

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27
Q

What is the epicardium’s location?

A

The outer layer of the wall (attaches to visceral pericardium)

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28
Q

What are intercalated discs?

A

Exclusive to the heart, they connect myocytes (muscle cells) together.

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29
Q

What are gap junctions?

A

They are membrane channels that control ion and small cell movement.

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30
Q

What are desmosomes?

A

Proteins that glue cells together

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31
Q

What is a sarcomere?

A

A basic unit of muscle fibers: myosin slides along actin during a contraction, which requires ATP using calcium, troponin, and tropomyosin

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32
Q

The right atrium receives blood from where? (3)

A

Superior/inferior vena cava and the coronary sinus

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33
Q

The right ventricle receives and sends blood where?

A

Receives blood from the right atrium; sends blood to the lungs

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34
Q

The left atrium receives blood where?

A

The pulmonary veins

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35
Q

The left ventricle receives and sends blood where?

A

Receives blood from the left atrium; sends blood to rest of body

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36
Q

What is the purpose of the right and left atrioventricular valves?

A

The atrioventricular valves prevent backflow from the ventricles into the atria

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37
Q

What are the atrioventricular valves?

A

RT: tricuspid; LT: bicuspid (or mitral)

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38
Q

What is the purpose of the right and left semilunar valves?

A

Prevents backflow from the arteries into the ventricles

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39
Q

What are the semilunar valves?

A

RT ventricle: pulmonary; LT ventricle: aortic

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40
Q

What are pectinate muscles?

A

Parallel ridges in the atrial walls

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41
Q

What are trabeculae carneae?

A

Muscular ridges projecting from the inner surface of the ventricles (prevents suction)

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42
Q

What are chordae tendineae?

A

Fibrous cords connecting valve edges to the papillary muscles

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43
Q

What are papillary muscles?

A

Pillar-like muscles in ventricular walls and connects to chordae tendinae

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44
Q

What is the purpose of the papillary muscles?

A

Prevents inversion or closure of valves during contraction

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45
Q

What is the process of pulmonary circulation?

A

The exchange of O2 and CO2 in the lungs

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46
Q

Describe the steps of pulmonary circulation — DEOXYGENATED blood (8)

A
  1. Superior/inferior vena cava
  2. RT atrium
  3. >>Right atrioventricular valve (tricuspid)>>
  4. RT ventricle
  5. >>Pulmonary valve>>
  6. Pulmonary trunk
  7. RT/LT pulmonary arteries
  8. Lung capillaries (exhale CO2)
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47
Q

Describe the steps of pulmonary circulation — OXYGENATED blood (7)

A
  1. Pulmonary capillaries (inhale O2)
  2. LT atrium
  3. >>LT atrioventricular valve (bicuspid/mitral)>>
  4. LT ventricle
  5. >>Aortic valve>>
  6. Aorta
  7. Rest of body
48
Q

Nodal cells make up?

A

Specialized muscle cells that ignite the myocytes (spreading APs through heart)

49
Q

What is polarization?

A

When the cell is at rest

50
Q

What is depolarization?

A

When the action potential takes place

51
Q

What is repolarization?

A

The return phase to polarization

52
Q

What is systole also known as?

A

Heart contraction

53
Q

What is diastole also known as?

A

Heart relaxation

54
Q

What are some things involved in the cardiac cycle? (5)

A

Electrical events, pressure changes, heart sounds, volume changes, mechanical events

55
Q

What is the function of the SA (sinoatrial) node?

A

The SA node is the pacemaker: it initiates depolarization and then atrial contraction

56
Q

Where is the SA node?

A

Posterior wall of the RT atrium

57
Q

What is the function of the AV node?

A

The AV node initiates ventricular depolarization

58
Q

What is the function of the Bundle of His?

A

The Bundle of His causes depolarization of the interventricular septum

59
Q

What is the function of the LT/RT Purkinje fibers?

A

Depolarizes/contracts LT and RT ventricles

60
Q

What is the travel path of the conductive pathway? (4)

A

SA node; AV node; Bundle of His; LT/RT Purkinje fibers

61
Q

The P wave represents?

A

The P wave represents atrial depolarization

62
Q

The QRS complex represents?

A

The QRS complex represents the depolarization and contraction of the ventricles

63
Q

The T wave represents?

A

The T wave represents the repolarization of the ventricles

64
Q

What is the cardiac cycle?

A

A series of pressure changes in the heart chambers, resulting in movement of blood

65
Q

What does atrial systolic pressure cause?

A

Blood moves from atria to ventricle via AV valves

66
Q

What happens during the atrial filling phase? (atrial diastolic pressure)

A
  • RT atrium fills with blood from inferior/superior vena cava
  • LT atrium fills with blood from pulmonary veins
67
Q

What happens to the heart’s blood flow in relation to ventricular systolic pressure?

A
  • Ejected from LT ventricle → through aortic valve → aorta → rest of body
  • Ejected from RT ventricle → through pulmonary valve → pulmonary trunk → lungs
68
Q

What happens during the ventricular filling phase? (diastolic ventricular pressure — 5 to 7 mmHg)

A

Blood fills ventricles from atria

69
Q

What does the S1 sound represent?

A

Closure of AV valves

70
Q

What does the S2 sound represent?

A

Closure of semilunar valves

71
Q

What does the S3 sound represent?

A

(Abnormal) AV valves open and ventricles rapidly fill with blood

72
Q

What does the S4 sound represent?

A

(Abnormal) Associated with atrial contraction and always pathological

73
Q

What is end diastolic volume?

A

Volume of blood in RT/LT ventricle at end of diastole filling

74
Q

What is end systolic volume?

A

Amount of blood remaining in ventricle after systole end

75
Q

What is cardiac output (CO)?

A

Volume of blood ejected from LT/RT ventricle at end of systole per min

76
Q

What is ejection fraction?

A

Percentage of blood ejected from LT ventricle during systole (55-70 %)

77
Q

What is the atrial contraction period?

A

Contraction of the atria after electrical stimulation

78
Q

What is the isovolumetric period?

A

Ventricular systole starts (all valves close, then ventricular contractions) — blood volume remains constant in ventricles

79
Q

What happens in the ventricular ejection period?

A

Ventricles eject blood to large blood vessels (AV valves are closed)

80
Q

What are the phases in ventricular systole? (2)

A

Isovolumetric contraction, ventricular ejection

81
Q

What is the isovolumetric relaxation period?

A

Aortic and pulmonary valves close (S2 sound) after ventricular pressure drop below diastolic aortic/pulmonary pressures. (beginning of diastole)

82
Q

What is the ventricular filling period?

A

AV valves open and ventricular filling starts

83
Q

What are the phases in the relaxation period? (2)

A

Isovolumetric relaxation, ventricular filling

84
Q

What is stroke volume?

A

Amount of blood ejected per beat

85
Q

What is contractility?

A

Inherent strength of heart’s contraction in systole

86
Q

What is preload?

A

Strength of muscles (which is dependent on amount of blood coming in to RT ventricle) before pumping at end of diastole

87
Q

What is afterload?

A

Resistance heart needs to overcome during/after aortic contraction in order to eject blood from ventricles

88
Q

What are the hormones involved in heart rate regulation? (2)

A

Epinephrine, norepinephrine

89
Q

What are the ions involved in the heart?

A

Sodium, potassium, calcium

90
Q

What is known as the aging pigment?

A

Lipofuscin

91
Q

What happens to the heart as you age? (3)

A

Deposits of lipofuscin; heart muscles degenerate; heart valves thicken/stiffen

92
Q

How is a person’s sex related to the heart?

A

Size of heart and major blood vessels are smaller in females

93
Q

How does physical fitness affect the heart?

A

Muscles can pull O2 from blood easier (reducing need to pump) and reduces stress hormones

94
Q

What are the nerves involved with the heart? (3)

A

Vagus, sympathetic, parasympathetic nerves

95
Q

What is directly related to increasing cardiac output? (2)

A

Increased stroke volume and heart rate

96
Q

What increases your heart rate? (3)

A

The nervous system (📈 sympathetic, 📉 parasympathetic); chemicals; other factors (age, sex, fitness, temperature)

97
Q

What increases stroke volume? (3)

A

Increased preload; increased contractility; decreased afterload

98
Q

What is coronary artery disease and its usual cause?

A

CAD is damage to the major blood vessels of the heart and its usual cause is plaque buildup (atherosclerosis) which limits blood flow (symptoms can vary)

99
Q

What is heart arrhythmia and when does it occur?

A

Improper beating of heart (either too fast aka tachycardia or too slow aka brachycardia) due to electrical impulses not working properly

100
Q

How can heart failure occur?

A

When the heart cannot pump (systolic) or fill (diastolic) properly… most common type is congestive heart failure

101
Q

What are some examples of what happens to your heart valve during heart valve disease? (3)

A

Stenosis: valve narrowing (can’t open right); regurgitation: loose leaflets (can’t close right); prolapse: leaflets stay open

102
Q

What is pericardial disease?

A

The heart’s pericardium inflames, which can cause pericardial friction (chest pain)

103
Q

What is cardiomyopathy and some symptoms?

A

Acquired/hereditary disease of the heart’s muscle. Symptoms include swollen legs/feet, bloated belly, and breathlessness.

104
Q

What is ischemia?

A

Inadequate blood/O2 flow to heart’s tissues

105
Q

What is angina?

A

Chest pain due to ischemia

106
Q

What is myocardia infarction?

A

Heart tissue death due to ischemia

107
Q

What is cardiac tamponade?

A

External pressure on heart (fluid in pericardial sac)

108
Q

What is carditis?

A

Inflammation of the heart

109
Q

What is the purpose of a blood test?

A

Shows muscle damage (troponin, lipid, cardiac enzymes)

110
Q

What is the purpose of an ECG?

A

ECGs tests cardiac electrical activity and detects things like arrhythmias

111
Q

What is the purpose of an echocardiogram (ultrasound)?

A

An echocardiogram checks valves and heart muscle contractions

112
Q

What is a coronary angiogram (catherization)?

A

XRAY that tests for coronary artery blockages

113
Q

What is a CCTA (coronary computed tomography angiogram)?

A

Imaging test that looks at the heart’s arteries

114
Q

What is a coronary angioplasty?

A

A procedure to improve blood flow to the heart

115
Q

What is thrombolytic therapy?

A

Medication preventing clot formation

116
Q

What does an artificial pacemaker surgery do?

A

Replaces SA or AV nodes