The coronary circulation in healthy and diseased states

Question 1

Layers of a blood vessel

Answer 1

Intima- endothelial cells
Media- smooth muscle cells
Adventitia- fibroblast, neural cells, vasa vasorum

Question 2

Course of the Rt Coronary artery

Answer 2

Rt Cusp -> RCA ->Rt Marginal branch ->Post Descending Artery

Question 3

The course of the Lt Coronary artery

Answer 3

Lt Cusp-> Lt main stem -> LAD
-> Lt circumflex -> Lt Marginal branch
-> Diagonal Branch

Question 4

LAD perfuses the…

Answer 4

majority of the anterior wall of left ventricle

Question 5

LCx perfuses the…

Answer 5

Lateral wall of the left ventricle

Question 6

RCA perfuses the…

Answer 6

Rt atrium and ventricle and the SA node and AV node

Question 7

Coronary perfusion pressure

Answer 7

= Aortic end-diastolic pressure - LV end-diastolic pressure

Question 8

Sympathetic stimulation causes

Answer 8

Tachycardia, increased contractility and increased afterload

Question 9

Vagal stimulation causes

Answer 9

Bradycardia, decreased contractility and decreased afterload

Question 10

Prostacyclin in coronary vasculature

Answer 10

Vasodilation and reduced platelet aggregation

Question 11

Thromboxane A2 in coronary vasculature

Answer 11

Vasoconstriction and increased plt aggregration

Question 12

Autoregulation of coronary vasculature

Answer 12

MAP 60-140

Question 13

Complications of myocardial infarction

Answer 13

• Acute MR secondary to papillary muscle rupture
• Anterolateral pap m- LAD - Post pap m- LCx or RCA
• VSD
• Free wall rupture

Question 14

Drugs ineffective after cardiac transplantation

Answer 14

• Ephidrene
• Atropine