The Citric Acid Cycle Flashcards
is the third stage of biomolecule catabolism
The Citric Acid Cycle
converts carbohydrates, lipids, and amino acids to carbon dioxide, water, and energy
The Citric Acid Cycle
The Citric Acid Cycle is a sequence of enzyme-catalyzed processes that take place in the?
mitochondria
When two carbons of acetyl CoA (CH3COSCoA) combine with an organic substrate that has four carbons to generate a six-carbon product, the citric acid cycle is?
initiated
joins with a four-carbon molecule catalyzed by the enzyme citrate synthase,
acetyl
releasing the group and forming a six-carbon molecule called citrate.
Oxaloacetate
citrate is converted into its?
isomer
citrate is converted into its isomer, isocitrate by the enzyme?
Aconotase
isocitrate is oxidized and releases a molecule of carbon dioxide, leaving behind a five-carbon molecule?
α-ketoglutarate
is a high-energy molecule similar to ATP, and its generation is unique to this specific step of the citric acid cycle.
guanosine triphosphate (GTP)
This enzyme converts succinate to fumarate with the help of flavin adenine dinucleotide (FAD) through transfering of Electrons forming FADH2
succinyl dehydrogenase
serves as a carrier of electrons and protons to the electron transport chain, where it participates in ATP synthesis.
FADH2
water is added to the four-carbon molecule fumarate, and with fumarase helping it catalyze hydration, converting it into another four-carbon molecule called?
malate
is an intermediate in the citric acid cycle and serves as a precursor for the regeneration of oxaloacetate in the subsequent step.
Malate
The oxidation of malate involves the transfer of electrons to the coenzyme NAD+, resulting in the formation of?
NADH