Coenzymes In Metabolism Flashcards
is the process by which the body converts food into energy
Metabolism
Coenzymes are molecules that play a crucial role in various biochemical reactions in the body. They work with enzymes to facilitate and regulate metabolic processes.
Coenzymes
act as cofactors, assisting enzymes in catalyzing reactions by providing necessary functional groups or transferring chemical groups between molecules.
Coenzymes
are important molecules in metabolism due to their role in facilitating enzyme activity, participating in metabolic pathways, and acting as carriers of chemical groups.
Coenzymes
The 4 important coenzymes in metabolism are:
- THIAMINE PYROPHOSPHATE
- NAD AND NADH
- FADH2 AND FAD
- COENZYME A AND COENZYME Q
Is a coenzyme derived from vitamin B1 that plays a crucial role in various metabolic pathways in the human body. This coenzyme is essential for the proper functioning of enzymes involved in carbohydrate metabolism, particularly in the citric acid cycle and the pentose phosphate pathway.
Thiamine pyrophosphate (TPP)
One of the primary functions of TPP is its role as a cofactor for enzymes involved in the citric acid cycle, also known as the?
Krebs cycle
This cycle is a central pathway in cellular respiration, where acetyl-CoA is oxidized to produce ATP, the energy currency of the cell. TPP is required for the activity of the enzyme pyruvate dehydrogenase, which converts pyruvate into acetyl-CoA, a key step in the citric acid cycle.
Krebs cycle
a metabolic pathway that generates NADPH and ribose-5-phosphate, essential for nucleotide synthesis and antioxidant defense.
pentose phosphate pathway
which is involved in this pentose phosphate pathway, requires TPP as a cofactor to transfer two-carbon units between sugars.
transketolase
TPP is involved in the metabolism of branched-chain amino acids, such as?
valine, leucine, and isoleucine
catalyzes the oxidative decarboxylation of valine, leucine, and isoleucine
alpha-keto acid dehydrogenase complex
which is part of the alpha-ketoglutarate complex, requires TPP as a cofactor for the conversion of alpha-ketoglutarate to succinyl-CoA.
alpha-ketoglutarate dehydrogenase
is one of the most abundant molecule in the body.
NAD (Nicotinamide Adenine Dinucleotide)
is involved in accepting and carrying electrons
NAD+