Coenzymes In Metabolism Flashcards

1
Q

is the process by which the body converts food into energy

A

Metabolism

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2
Q

Coenzymes are molecules that play a crucial role in various biochemical reactions in the body. They work with enzymes to facilitate and regulate metabolic processes.

A

Coenzymes

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3
Q

act as cofactors, assisting enzymes in catalyzing reactions by providing necessary functional groups or transferring chemical groups between molecules.

A

Coenzymes

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4
Q

are important molecules in metabolism due to their role in facilitating enzyme activity, participating in metabolic pathways, and acting as carriers of chemical groups.

A

Coenzymes

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5
Q

The 4 important coenzymes in metabolism are:

A
  • THIAMINE PYROPHOSPHATE
  • NAD AND NADH
  • FADH2 AND FAD
  • COENZYME A AND COENZYME Q
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6
Q

Is a coenzyme derived from vitamin B1 that plays a crucial role in various metabolic pathways in the human body. This coenzyme is essential for the proper functioning of enzymes involved in carbohydrate metabolism, particularly in the citric acid cycle and the pentose phosphate pathway.

A

Thiamine pyrophosphate (TPP)

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7
Q

One of the primary functions of TPP is its role as a cofactor for enzymes involved in the citric acid cycle, also known as the?

A

Krebs cycle

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8
Q

This cycle is a central pathway in cellular respiration, where acetyl-CoA is oxidized to produce ATP, the energy currency of the cell. TPP is required for the activity of the enzyme pyruvate dehydrogenase, which converts pyruvate into acetyl-CoA, a key step in the citric acid cycle.

A

Krebs cycle

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9
Q

a metabolic pathway that generates NADPH and ribose-5-phosphate, essential for nucleotide synthesis and antioxidant defense.

A

pentose phosphate pathway

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10
Q

which is involved in this pentose phosphate pathway, requires TPP as a cofactor to transfer two-carbon units between sugars.

A

transketolase

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11
Q

TPP is involved in the metabolism of branched-chain amino acids, such as?

A

valine, leucine, and isoleucine

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12
Q

catalyzes the oxidative decarboxylation of valine, leucine, and isoleucine

A

alpha-keto acid dehydrogenase complex

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13
Q

which is part of the alpha-ketoglutarate complex, requires TPP as a cofactor for the conversion of alpha-ketoglutarate to succinyl-CoA.

A

alpha-ketoglutarate dehydrogenase

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14
Q

is one of the most abundant molecule in the body.

A

NAD (Nicotinamide Adenine Dinucleotide)

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15
Q

is involved in accepting and carrying electrons

A

NAD+

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16
Q

is the form that donates electrons to fuel various biochemical reactions in the cell.

A

NADH

17
Q

NAD participates in reactions that involve the transfer of?

A

electrons

18
Q

NAD+ functions as an?

A

electron carrier

19
Q

it facilitates the transfer of electrons and hydrogen ions to generate ATP, the primary energy currency of the cell.

A

NADH

20
Q

During the oxidation of fuel molecules like glucose, fatty acids, and amino acids, NAD+ acts as an?

A

electron acceptor

21
Q

is a critical component that facilitates electron transfer processes within the cell.

A

The nicotinamide ring in NADH

22
Q

this ring is essential for accepting and transferring electrons during oxidation reactions, enabling the flow of electrons and supporting vital metabolic reactions.

A

nicotinamide ring

23
Q

NAD+ is a biological molecule composed of?

A

carbon, hydrogen, oxygen, nitrogen, and phosphorus atoms

24
Q

The formation of NAD involves a series of biochemical reactions known as the?

A

NAD biosynthesis pathway

25
Q

In this pathway, NAD is synthesized from simple compounds such as amino acids, tryptophan, and aspartic acid. The de novo pathway involves multiple enzymatic reactions that ultimately lead to the formation of NAD+

A

De Novo Pathway

26
Q

involves the recycling of nicotinamide, a breakdown product of NAD, to regenerate NAD. In this pathway, nicotinamide is converted back to NAD through a series of enzymatic reactions

A

salvage pathway

27
Q

FAD is derived from riboflavin, also known as?

A

vitamin B2

28
Q

which is an essential nutrient for plants and animals alike. It is usually found in chickens, meat , and poultry products

A

FAD

29
Q

The reduced form of the coenzymes NAD+ and FAD acts as a?

A

redox carrier

30
Q

formed during earlier stages of cellular respiration like the Krebs cycle, donates its electrons to the electron transport chain (ETC) in the inner mitochondrial membrane.

A

FADH2

31
Q

is involved in the transfer of acyl groups in numerous metabolic reactions making it essential for energy production and the synthesis of important molecules.

A

COENZYME A

32
Q

Its main function is to convey the carbon atoms within the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production.

A

COENZYME A IN CITRIC ACID

33
Q

it play a crucial role in the breakdown of fatty acid through a process known as beta-oxidation.

A

Coenzyme A in FATTY ACID METABOLISM

34
Q

also known as ubiquinone, derivative with long isoprenoid tail

A

COENZYME Q

35
Q

COENZYME Q also known as

A

ubiquinone