Energy And Metabolism Flashcards
is a series of proteins that transfer electrons from donors to acceptor
electron transport chain
is the process by which the energy released by these electrons is used to generate ATP, which is the cellular currency of energy.
oxidative phosphorylation
is the culmination of energy-yielding metabolism
Oxidative Phosphorylation
is the set of metabolic pathways that break down molecules into smaller units, releasing energy in the process.
catabolism
which are living organisms that require oxygen to carry out their metabolic processes
aerobic organisms
The primary goal of oxidative phosphorylation is to?
produce ATP
Complex I, also referred to as
NADH-CoQ oxidoreductase
serves as the starting point for electron transport within the mitochondria, the powerhouse of the cell. This complex is an integral component of the inner mitochondrial membrane, comprising a complex assembly of over 20 subunits.
NADH-CoQ oxidoreductase
within Complex I contains flavin mononucleotide
flavoprotein
a coenzyme distinct from flavin adenine dinucleotide (FAD) due to the absence of an adenine nucleotide.
flavin mononucleotide (FMN)
the reduced flavoprotein is?
re-oxidized
The electrons liberated from the iron-sulfur protein are then transferred to coenzyme Q (CoQ), also known as?
ubiquinone
is the second of the four membrane-bound complexes
Succinate
is also responsible for catalyzing the electron transfer to coenzyme Q.
CoQ oxidoreductase
What enzyme is succinate dehydrogenase?
Flavin enzyme
converts succinate to fumarate as part of the citric acid cycle.
succinate dehydrogenase
succinate dehydrogenase is a component of a complex that also includes
two iron-sulfur proteins
Complexes I, III, and IV of the electron transport chain are?
proton pumps
carries the electrons to complex IV, where a final batch of H+ ions is pumped across the membrane.
cytochrome C (cyt C)
Complex III of the electron transport chain, also known as?
Q-cytochrome c oxidoreductase or simply cytochrome reductase
is a multi-subunit structure that functions to accept electrons from ubiquinol and transfer them onto another electron
carrier called cytochrome c.
cytochrome reductase
contains a single heme group
cytochrome c1
that consists of two different heme groups
cytochrome b
that contains the 2Fe-2S center
Rieske center
The process by which the electrons are transferred from the ubiquinol to cytochrome c is known as the
Q cycle
Q cycle actually consists of two mini-cycles called?
half-cycles
a ubiquinol molecule attaches onto complex III and transfers the two electrons to the complex.
first half-cycle
is composed of cytochrome proteins c, a, and a3
fourth complex
hold an oxygen molecule very tightly between the iron and copper ions until the oxygen is completely reduced
cytochromes
The final stage of the electron-transport chain is the oxidation of the reduced cytochrome c generated by?
Complex III
is reasonably well understood at the structural level. It consists of 13 subunits, of which 3 (called subunits I, II, and III) are encoded mitochondrial genome
Bovine cytochrome c oxidase
All of the protein complex is known as?
ATP synthase
All of the protein complex is known as ATP synthase. It is also referred to as?
mitochondrial ATPase
was identified prior to the ATP production reaction
hydrolytic process
American scientist Paul Boyer of UCLA and British scientist John Walker of the Medical Research Council in Cambridge, England, received the 1997 Nobel Prize in Chemistry for their work figuring out the
structure and function of ATP synthase
England, received the 1997 Nobel Prize in Chemistry for their work figuring out the structure and function of this enzyme.
Paul Boyer and John Walker
received the other half of this prize for his work on the sodium-potassium pump, which also serves as an ATPase.
Jens Skou
was the mechanism that first sparked all of the arguments; later, conformational coupling was also taken into account
Chemiosmotic coupling
According to him, the chemiosmotic model is a model for linking energy.
Peter Mitchell
is a model for linking energy.
chemiosmotic model
Mitchell described enzymatic processes as?
chemiosmotic
means the obligatory link between ATP production in mitochondria and the respiratory chain’s electron flux; neither of the two Without each other, processes can continue.
coupling