The Circulatory system Flashcards

1
Q

What’re the three main parts of the circulatory system

A

Fluid, Tubes, Pump

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2
Q

What is the fluid part of the circulatory system

A

Blood, made up of plasma and bloods cells

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3
Q

What are the tubes in the circulatory system

A

arteries, Arterioles, veins, veinules, capillaires

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4
Q

What is the pump in the circulatory system

A

The heart

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5
Q

What are the functions of the circulatory system

A
  • transport oxygen and carbon dioxide gases
  • transport nutrients and wastes
  • body temp regulation
  • transport of hormones
  • protection against foreign toxins and infections
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6
Q

How much litres of blood does the average person have? How much of that is plasma and how much of it is blood cells?

A

5 litres

55% is plasma, 45% is blood cells

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7
Q

what’re the two components of blood

A

Plasma, Erythrocytes (RBC)

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8
Q

Describe Plasma

A
  • 90% water
  • Contains dissolved nutrients, waste, gases, hormones, salts, protein and anti-bodies
  • Used to transport substances throughout the body
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9
Q

Describe RBC

A
  • Made in bone marrow, stored in spleen
  • No nuclei (room for more oxygen) or mitochondria (can’t reproduce)
  • 120 day life span
  • Hemoglobin molecule (4 Fe atoms) binds oxygen
  • Bi-concave shape gives cell flexibility to move through blood vessels
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10
Q

What is an Erythrocyte

A

RBC

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11
Q

In mammals, what’re the two factors that control when oxygen is picked up and when it is released by hemoglobin

A
  1. Concentration of oxygen in the blood

2. Acidity in the blood

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12
Q

Explain why concentration of oxygen in the blood control when oxygen is picked up and when it is released by hemoglobin

A

measured as a partial pressure (kPa), when partial pressure is low (muscles that are active ) hemoglobin will release oxygen

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13
Q

Explain why Acidity in the blood control when oxygen is picked up and when it is released by hemoglobin

A
  • presence of carbon dioxide forms carbonic acid in blood
  • carbon dioxide is the waste product of cellular respiration
  • The more acidic the blood, the more oxygen is needed by the cells
  • high acidity weakens the chemical bond between oxygen and hemoglobin
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14
Q

Why are cold blooded animals (lizards, snakes, etc) sluggish in cold temps

A

In cold temps hemoglobin releases oxygen more slowly. (question) because little oxygen is getting to cells for cellular respiration

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15
Q

What are Leucocytes

A

WBC

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16
Q

Describe Leucocytes

A
  • consume and destroy invading bacteria, damaged cells and toxins
  • made in bone marrow
  • fewer in numbers than RBC
  • Elevated WBC count may indicate infection
  • some consume invaders and destroy themselves with digestive enzymes, while others produce anti-bodies
17
Q

What is pus

A

living and dead WBC and bacteria

18
Q

what is leukemia

A

disease when WBCs divide out of control

19
Q

what is macrophages

A

phagocytic cells that pass through capillary walls to engulf and digest pathogens; belong to the innate immune response (generalized response)

20
Q

what are lymphocytes

A

non phagocytic cells that take part in the acquired immune response (specific response).

21
Q

what are the two main types of lymphocytes and where they mature/come from

A
  1. T-cells mature in the thymus gland

2. B cells from bone marrow

22
Q

what is a monocyte

A
  • WBC

- migrate from the bloodstream to other tissues and differentiate into tissue resident macrophages

23
Q

what is eosinophil

A
  • WBC

- attack parasites and part of allergic response

24
Q

what is a neutrophil

A
  • WBC

- target bacteria and fungal infections

25
Q

what is a antigen

A

a foreign substance that triggers immune response (typically a protein on the cell wall or protein coat of an invading microbe)

26
Q

what is an anti body

A

produced in the body as a response to the antigen, act as a marker or destroy

27
Q

explain immune response

A

General response:
1. bacteria breaks through the skin barrier
2.Basophil and most cells ( both WBC) release histamine at site of infection to start inflammation
3. The infection site becomes swollen due to increased blood flow. More blood cells come to infection site looking for the foreign antigen. This increases temp which could kill bacteria
4. Macrophages arrive at site to kill bacteria
5. Macrophages share evidence found with immune response
Learned Response:
6. T-cells take info from macrophages and process it. Then they produce a small army (killer Ts)
7. B-cells recognize foreign antigen and produce plasma (which makes anti bodies) and memory B-cells (which recognizes the bacteria in future situations and can make the immune response go immediately into anti-body response instead)

28
Q

What is a thrombocyte

A

a platelet

29
Q

Thrombocytes are special cells that have broken off of what

A

bone marrow cells (no nuclei)

30
Q

what are thrombocytes used in

A

blood clotting

31
Q

what do thrombocytes do for blood clotting (3 steps)

A
  • adhere to broken blood vessel surface, secrete chemicals to attract other platelets to the site, platelets form a plug upon which a fibrin mesh (protein net) forms
  • break open edges release fibrinogen into plasma, reacts with clotting factors
  • strands of fibrin form a mesh clot that contracts and begins to close the wound
32
Q

what is a scab

A

fibrin, platelets (thrombocytes), blood cells

33
Q

what is aspirin

A

recommended in low daily dosage for some adults to reduce risk of blood clots as it prevents platelets from sticking together