the autonomic nervous system Flashcards
components of the nervous system
central
peripheral
components of the peripheral system
efferent
afferent
components of the efferent nervous system
somatic
autonomic
components of the autonomic nervous sytem
sympathetic
parasympathetic
functions of the autonomic nervous system
maintenance of body integrity in the environment
smooth muscles, glands, heart and energy ependiture
- temperature
- blood pressure
- food digestion
- labour
sympathetic system
fight and flight
parasympathetic system
rest and digest
dopamine
precursor of noradrenaline
how to interfere with signaling
synthesis
effector
breakdown
mimetics
mimick or stengthen the endogenous release (agonist)
lytics
counteract effects of endogenous release (antagonist)
adrenergic receptors
a1, a2
b1,b2,b3
cholinergic receptors
nicotinic receptors (skeletal, central, autonomic) muscarinic receptors (M1-M5)
how is noradrenaline made
tyrosine –> L-dopa–> dopamine –> noradrenaline
mono-amino-oxidase
breaks down noradrenaline
a2 receptor
gives negative feedback signal to the presynaptic neuron
affinity of noradrenaline
a1,a2 and b1
affinity of adrenaline
a1,a2,b1 and b2
b2-receptor
presynaptic receptor that stimulates the presynaptic neuron for noradrenaline release. causes casodilatation
a1 receptor
leads to vasoconstriction
affinity of isoprenaline
b1 and b2
