Receptor response Flashcards

1
Q

endogenous signaling molecules

A

hormones
neurotransmitters
cytokines

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2
Q

substances that bind to the ionchannel

A

GABA or glutamate

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3
Q

substances that bind tot the G-protein coupled receptors

A

(nor)adrenalin

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4
Q

substances that bind to the kinase receptors

A

insulin and growth factors

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5
Q

substances that bind tot the nuclear receptors

A

steriods

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6
Q

competitive antagonists

A

will compete with the agonist, but after a high concentration of the agonist it can overcompete the antagonist.

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7
Q

non-competitive antagonists

A

bind to the receptor and the nthe receptor is not available anymore for agonists

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8
Q

allosteric binding

A

different binding site to the main binding site wehere drugs can bind. they can induce different conformations or prevent the active conformaton to take place. It can not be competed away by the agonist.

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