Testicular tumours Flashcards

1
Q

Who gets it

A

Young male adults

Males with undescended testes

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2
Q

Types

A

Seminoma

Non-seminomatous germ cell tumour (teratoma)

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3
Q

Teratoma is more common than seminoma. True or false?

A

False

- seminoma is more common

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4
Q

Seminoma - age

A

33-50

- rare to develop this before puberty

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5
Q

Seminoma - pathology

A

Solid, pale, looks like a potato

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6
Q

Seminoma is more likely to spread than teratoma - true or false?

A

False

- teratoma is more likely to spread

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7
Q

Non-seminomatous germ cell tumour - age

A

20-30

- can occur before puberty

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8
Q

Non-seminomatous germ cell tumour - wide variety of tissue types are seen. True or false?

A

True

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9
Q

Clinical features

A

Painless testicular swelling
Slow progression
Non tender
Gynaecomastia

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10
Q

Clinical examination

A

Hard
Craggy
Stone like

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11
Q

Investigation of choice

A

US

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12
Q

Investigations

A

US
Markers
CT scan

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13
Q

Markers - if increased these are highly suggestive of testicular tumour. True or false?

A

True

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14
Q

Markers - in which type of testicular germ cell tumour is AFP raised in?

A

Non-seminomatous germ cell tumour

  • never raised in seminoma
  • mainly raised in yolk sac tumours
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15
Q

Markers - in which type of testicular germ cell tumour is beta HCG most commonly raised in?

A

Non-seminomatous germ cell tumour is more common

- also raised in pure seminoma

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16
Q

Markers - LDH

A

General tumour marker

17
Q

Markers - PLAP

A

Placental alk phosphatase

- monitors patients with seminoma

18
Q

Where is metastatic spread most common?

A

Embryological location of the testes

  • auto-caval nodes
  • para-aortic lymph nodes
19
Q

Management

A

Very sensitive to radiotherapy and chemotherapy

Orchidectomy
- inguinal approach

20
Q

Seminoma is more RADIO/CHEMO -sensitive than non-seminomatous?

A

Radio

21
Q

Non-seminomatous is more RADIO/CHEMO -sensitive than seminoma?

A

Chemo