Testicular tumors Flashcards
Painless, homogenous testicular enlargement with increased placental ALP
Seminoma
Yellow, mucinous. Presence of schiller duval bodies that resemble primitive glomeruli. Increased AFP
Yolk sac (endodermal sinus) tumor
Disordered synchytiotrophoblastic and cytotorphoblastic elements with hematogoeous metastases to lungs and brain. What is increased and what symptom can it cause from that being increased?
hCG is increased. can resemble hyperthyroidism because structurally similar to LH FSH TSH)
teratoma has what increased value?
increased hCG and/or AFP in 50% of cases
hemorrhagic mass with necrosis; painful; worse prognosis than seminoma with often glandular/papillary morphology
Embryonal carcinoma
Contains reinke cyrstals (eosinophilic cytoplasmic inclusions) with golden brown color
Leydig cell tumor
Androblastoma from sex cord strom
sertoli cell tumor
Most common testicular cancer in old men that is not a primary cancer
Testicular lymphoma that arises from metastatic lymphoma to testes. aggressive
What increases risk of prostate cancer genetically?
BRCA1 BRCA2 presence