test 6 Flashcards
Cell properties (5)
- Smallest living unit of organization in the body
- Each cell has a cell membrane, cytoplasm, organelles, and inclusions (can function without the aid of other cells)
- Cells interact with one another
- Cells with similar characteristics are grouped to form a tissue
- Various tissues are bound together to form an organ
cell > tissue > organ
define exocytosis
Active transport of materials from a vesicle within the cell to the extracellular environment
define endocytosis
The uptake of materials from the extracellular environment into the cell
define phagocytosis
engulfing/digesting solid waste and foreign materials by the cell through enzymatic breakdown of materials
what are the 4 basic tissues
Epithelial
Nervous
Muscle
Connective
define regeneration
Natural renewal of the tissue (dead cells are removed from the new tissue and new ones take their place)
define turnover time
The time newly divided cells take to be completely replaced (Aging and disease delay or prevent this process)
why is it important we understand the histology of basic tissues
To understand the pathological process of renewal/repair/aging of tissues and what that might look like clinically
what are the types of epithelium
Simple: squamous, cuboidal, columnar, pseudostratified
Stratified: squamous (keratinized, nonkeratinized), cuboidal, transitional
what are the types of connective tissue
Solid soft: connective tissue proper, specialized tissue (adipose, fibrous, elastic, reticular)
Solid firm: cartilage
Solid rigid: bone
Fluid: blood, lymph
epithelium
Tissue that _____ and _______ the _______ and _____ body surfaces
Functions: (5)
_____ or _________: can be different degrees
Renewal rates: _____ for epithelial tissue. ______ and ________ occur at the same rate
Tissue that COVERS and LINES the INTERNAL and EXTERNAL body surfaces
Functions: protective, covering, absorption, secretion, and sensory
Keratinized or nonkeratinized: can be different degrees
Renewal rates: HIGH for epithelial tissue. Mitotic activity and shedding occur at the same rate
Epithelium histology
_____ grouped cells surrounded by little or no _____ or ______
Capable of _______, ________ regenerative
_______: no blood supply of its own; gets blood from __________
Closely grouped cells surrounded by little or no intercellular substance or tissue fluid
Capable of renewal, HIGHLY regenerative
Avascular: no blood supply of its own; gets blood from connective tissue
Epithelium classification
Un-stratified (SIMPLE): _____ layer
Pseudostratified: cells are _____ and seem ______ but all are attached to the _________
Stratified epithelium: _______ layers; ______ epithelium (stretches)
un-stratified (SIMPLE):
- Single layer
- Simple squamous/cuboidal/columnar epithelium
Pseudostratified:
- cells are closely packed and seem arranged in layers but all are attached to the basement membrane
Stratified epithelium
- Two or more layers
- transitional epithelium (stretches)
Pseudostratified epithelium
Falsely appears to have multiple layers under low power magnification
On high power magnification, one can see that cells are on the same level but the nuclei are at different levels
types of epithelial cells
squamous
Flat (ex: endothelium)
Cuboidal
Cube-shaped (equal height, equal width) (ex: salivary gland)
Columnar cells
rectangular/tall cells (ex: salivary glands)
how many layers are in the basement membrane
what does each layer consist of
2 layers: basal lamina and reticular lamina
basal lamina: lamina lucida and lamina densa
reticular lamina: collagen fibers
BASEMENT MEMBRANE
______ structure located between _______ and __________
__________ (Superficial layer)
_________: close to epithelium
_________: close to connective tissue
_________ (deeper layer) : Deeper portion consisting of _______ produced by the underlying _______
Acellular structure located between epithelium and connective tissue
Basal lamina (Superficial layer)
Lamina lucida: close to epithelium
Lamina densa: close to connective tissue
Recticular lamina
Deeper portion consisting of collagen fibers produced by the underlying connective tissue
connective tissue
Most _____ type of basic tissue in the body by _____
Functions: (8)
Serves as a source of _______ to the ______
Besides cells and fibers, it contains _____ and _______
_______ and ________
Most abundant type of basic tissue in the body by weight
Functions: support, attachment, packing, insulation, storage, transport, repair, defense
Serves as a source of nutrients to the epithelium (blood supply)
Besides cells and fibers, it contains nerves and blood vessels
Renewable and vascular
connective tissue histology
_____ are the most common cell type in CT
- Synthesize _______ and _______
- Depending on the degree of mineralization, collagen tissues may be ____, _______, or _____
- It also is abundant in: (5)
- Can be more _____ when _______ (repair)
Different types of ______ fibers are found in CT histology
- ______ fibers: The most common collagen protein is _____ collagen which includes ______, ______, _______
- ________ fibers: occur in a very _____ type of tissue (soft palate)
- ______ fibers: forming a _____ in the tissue (lymph nodes)
Fibroblasts are the most common cell type
- Synthesize (make) collagen and intercellular substance
- Depending on the degree of mineralization, collagen tissues may be rigid (bone), compliant (tendon), or have a gradient from rigid to compliant (cartilage). It also is abundant in corneas, cartilage, bones, blood vessels, and dentin in teeth
- Can be more active when stimulated (repair)
Different types of protein fibers are found in CT histology
- Collagen fibers: The most common collagen protein is type 1 collagen which includes fibroblasts, osteoblasts, and odontoblast
- Elastic fibers: occur in a very elastic type of tissue (soft palate)
- reticular fibers: forming a network in the tissue (lymph nodes)
loose connective tissue
The superficial layers of the _____ and ______
Serves as _______ for deeper structures
No prominent _______ elements
The superficial layers of the skin dermis and lamina propria (basement membrane) of the oral mucosa
Serves as protective padding for deeper structures
No prominent connective tissue elements
dense CT
Deep to ______
______ packed with a more ______ arrangement
Primarily ______ fibers to give it ______
Deep to loose connective tissue
Tightly packed with a more regular arrangement
Primarily collagen fibers to give it strength
CT turnover time and repair
Turnover is due to the production of _______ and _________ by ________
With injury, CT goes through __________
First immature CT, known as ________tissue, forms and eventually matures of_____ fibers increase
Turnover is due to the production of fibers and intercellular substance by fibroblasts
With injury, CT goes through healing stages
First immature CT known as granulation tissue forms and eventaully matures of collagen fibers increase
specialized CT
- _______ connective tissue
Found in _____ beneath the skin and around ______ - ________ connective tissue
Provides _____ (like vocal cords) - _______ connective tissue
Forms the supportive framework/network of _________
- Adipose connective tissue
Found in fatty tissue beneath the skin and around organs and joints - Elastic connective tissue
Provides stretching (like vocal cords) - Reticular connective tissue
Forms the supportive framework/network of blood vessels and internal organs
cartilage (solid form)
Composed of ____ and a _____
Matrix is composed of primarily _____
what is the perichondrium
_______ : receives nutrients from the _______
_________ CT
Two types of cells (describe them)
1.
2.
Present in the ____
Composed of cells and a matrix
Matrix is composed of primarily collagen
Perichondrium: the CT surrounding most cartilage
Avascular: receives nutrients from the perichondrium
Nonmineralized CT
Two types of cells
1. Chondroblasts: immature, produce matrix
2. Chondrocytes: mature chondroblasts
Present in the TMJ