Test 4: Virus and Fungus Flashcards
What are the symptoms of the Measles virus (Rubeola; red measles)?
- High Fever
- Cough
- Rhinitis
- Red Eyes
- Macropapular rash (3-5 days after onset of symptoms)
The symptoms for Measles occur how long after exposure and last for how long?
10-12 days after exposure
7-10 day length
What is the contagious period for Measles?
4 days prior to 4 days after start of symptoms or rash
What are some secondary complication seen in about 30% of Measles cases?
Diarrhea
Blindness
Inflammation of Brain
Pneumonia
How is Measles diagnosed?
Immunodiagnosis
Clinical signs and symptoms
Mumps virus (parotitis)- infection of the parotid glands has what symptoms?
Fever Muscle pain Headache Fatigue usually followed by swelling of parotid glands
The symptoms for Mumps occur in what time frame after exposure and resolve after how many days?
16-18 after exposure
Resolve in 4-10 days
What is the contagious period for Mumps?
Few days prior to 4 days after symptoms
What complications are associated with Mumps virus?
Meningitis
Pancreatitis
Permanent Deafness
Testicular/Ovarian swelling
Symptoms for Mumps virus are more severe in what population?
Adults more than children
How is Mumps diagnosed?
Immunodiagnosis
Clinical signs and symptoms
What are the symptoms of the Rubella virus (German Measles or 3-day measles)?
Mild Fever Rash (Face then body) Sore Throat Fatigue Swollen lymph nodes
The symptoms for Rubella virus occur how long after exposure and resolve in what time frame?
14 days after exposure
Resolve 2-3 days
What is the period of time in which a person is contagious when infected with Rubella?
7 days prior to start of symptoms to the end of rash
What complication are seen in Rubella infections?
Bleeding Problems
Inflammation of nerves
Congenital rubella syndrome (CRS) during early preg.
Diagnosis of Rubella can be made how?
Immunodiagnosis
Clinical Signs and symptoms
Human Herpes virus-6 and -7 cause what?
- Roseola (Exanthum Subitum; Sixth Disease): Fever and Rash
- Neuroinflamtory disease: multiple sclerosis, encephalitis, pneumonitis
How does the Human Herpes virus-6 and -7 gain entry into the nervous system?
Via Olfactory tissues
What may serve as a reservoir of the Human Herpes virus-6 and -7?
Salivary glands
Parvovirus B19 is a very small non-enveloped DNA virus that causes what?
Fifth Disease or Erythema infectiosum
Chronic anemia in AIDS patients
Arthritis lasing 1-3 weeks up to several months Miscarriage due to severe fetal anemia
What is Fifth Disease or Erythema infectiosum?
- Childhood Rash disease (Slapped Cheek Syndrome), most common in 6-10 year olds
- Symptoms: 6 days (4-14days) after exposure last a week
- Named due to: 5th most common cause of pink-eye
How is Parvovirus B19 Transmitted?
Infected respiratory droplets
Parvovirus B19 only infects humans and outbreaks occur where and how often?
Nurseries and Schools
Every 3-4 years
Molluscum Contagiosum Virus (MCV), is a DNA poxvirus MCV-1 to -4, MCV-1 and MCV-2 are most prevalent in what age groups?
MCV-1: 1-11 year olds
MCV-2: Adults
What does MCV cause?
Mucous membrane lesions or “Water warts” on the skin
- Most common: Trunk, arms, groin, legs
- Transmitted by touching affected skin
What is the etiologic agent of Smallpox?
Variola major (orthopox family) DNA virus
What is the synchronous progression of the smallpox rash?
Rash-macules-> Vesicles-> Pustules-> Scabs
The rash for smallpox begins where and progresses where?
Face, hands, forearms, and spreads to lower extremities in 7-16 days
Where are lesions seen when infected with smallpox?
Palms of hands
Soles of feet
In the mouth
What is the mortality rate for smallpox?
30%
When collecting a specimen sample what is the process for smallpox vesicles or pustules?
Scrape the base of vesicle or pustule & make a touch prep on microscope slide
When collecting a specimen sample what is the process for smallpox scab lesions?
Remove as many scabs as possible and place in screw-capped plastic tube
What are the diagnostic test to rule out varicella-zoster virus?
DFA/IFA and PCR
What diagnostic test is Variola-specific?
PCR
What yeast is normal flora of the mouth, throat, large intestine, vagina, and skin?
Candida Albicans