Test 2c Flashcards
Chronic degenerative condition with “wear and tear” on joints
Osteoarthritis
What in particular does osteoarthritis affect?
Articular cartilage
What happens to the bone from osteoarthritis
Thickens
Which type of arthritis is more common in women?
RA
Chronic and inflammatory auto-immune arthritis
RA
Inflamed and thickened synovial membrane erodes articular cartilage and forms scar tissue
Pannus
What specifically happens to during RA
Inflammatory cells from blood enter joint cavity and release chemicals that destroy body tissues
Uric acid accumulates in blood and deposits as needle shaped crystals in the soft tissues of the joints
Gout
Bone thinning disease that results in fragile bones that fracture easily
Osteoporosis
Causes of osteoporosis
Poor intake of calcium and protein, lack of vitamin D, insufficient weight bearing exercise, parathyroid disease
Vitamin D deficiency as a result of inadequate exposure to sunlight and poor dietary intake
Rickets
WHat happens during rickets
bending of the bones at the cartilage, shaft junction due to shaft weakness
Progressive neoplastic disease of marrow plasma cell tumors
Multiple myeloma
Most common bone cancer other than MM
Osteogenic sarcoma
Where does osteogenic sarcoma usually metastasize to?
Lungs
Where is osteogenic sarcoma most common?
knee
What kind of bones are especially vulnerable to ewing’s sarcoma?
Extremities
Essential function of muscular tissue
Contract or shorten
3 types of muscle tissues
smooth, cardiac, skeletal
Anchor muscles to bone, cartilage or connective tissue
Tendons
General schematic of muscle
Thousands of fibers bundled together by connective tissue
Skeletal muscle function
Produces movement, blood return
What are muscle fibers individually wrapped in
Endomysium
What are multiple muscle fibers wrapped in?
Perimysium
What is a bundle of multiple muscle fibers called
Fascicle
What are many fascicles bound together by
Epimysium
Chains of contractile muscle units
Sarcomere
Sarcomeres are aligned ________ the entire length of myofibril
End to end
What does arrangement of myofilaments produce?
Banding pattern
Thick muscle filaments
Myosin filament
Thin muscle filaments
Actin filament
4 unique properties of muscle tissues
excitability, contractility, extensibility, elasticity
Property of muscle tissues that is able to receive stimulus
excitability
Propertry of muscle tissues that is able to shorten
contractility
Propertry of muscle tissues that is able to be stretched
extensibility
Propertry of muscle tissues that is able to recoil to resting length
elasticity
What is the muscular system stimulated by
nerve impulses
What makes up a motor unit
One neuron and all of the skeletal muscle cells it stimulates
Long extension from neuron cell body that goes to the muscle
axon
tiny branches of axon that form junction with the sarcolemma of muscle cells
Axon terminal
Junction of axon terminal and sarcolemma
Neuromuscular junction
Gap between axon terminal and muscle cell sarcolemma
synaptic cleft