Test 1: Subcutaneous Mycoses Flashcards
Subcutaneous mycoses can effect which 4 areas of the body?
Deep layers of skin
Muscle
Bone
Connective Tissues
Subcutaneous mycoses infections are
______ and _______ in nature
SubQ mycoses infections are
chronic and insidious in nature
Sporotrichosis is caused by
________ ________
Sporothrix schenckii
Sporothrix schenckii
causes sporotrichosis in which 4 animals?
Humans
Horses
Dogs
Cats
Which subcutaneous mycoses associated pathogen causes
*epizootic lymphagitis *in equines
Histoplasma capsulatum var. farciminosum
Which agents cause oomycosis
which is the cause of a variety of diseases in
*fish *and mammals?
- Aphanomyces*
- Lagenidium*
- Pythium*
- Saprolegnia*
Sporothrix schenckii
is a
saprophytic ____ fungi
saprophytic dimorphic fungi
T/F
Sporotrichosis is a common disease that manifests as
chronic, ulcerative lymphangitis
of the skin and subcutis
FALSE
Sporotrichosis is a RARE disease
Systemic diseases
caused by Sporothrix schenkii
occur frequently in which non-human mammalian species?
Sporothrix schenkii causes systemic disease commonly in
cats
The following virulence factors are associated with which subcutaneous mycoses causing pathogen?
- Adhesins and Proteases*
- Chitin, Ergosterol, Lipids, Melanin, Peptide-rhamnomannan, sialic acids (cell wall factors)*
Sporothrix schenckii
What is the main reservoir for Sporothrix schenckii?
Plant Material and Soil
Worldwide
Occasionally, this subcutaneous mycoses causing pathogen is
isolated from the *mucous membranes *
of normal animals
Sporothrix schenckii
Sporothrix schenckii
is usually transmitted through skin contact afflicted by trauma
but can occasionally be transmitted through
__________ or _________
inhalation or ingestion
**Exudates **can present high numbers of Sporothrix schenckii
in which species?
CATS
Lesions caused by Sporothrix schenckii
are
_______________
pyogranulatamous
Pyogranulatamous lesions have prululent centers
surrounded by
what 4 types of cells?
Epitheliod cells
Giant cells
Lymphocytes
Plasma cells
In the last step of pathogenesis of Sporothrix schenckii
dissemination can occurs to the
viscera, joints, and CNS
in which species?
CATS
Direct examination of lesions of Sporothrix schenckii
is often unrewardings except in
________
which contain
abundant yeast cells
CATS
Because direct examination of exudates is unrewarding when dealing with Sporothrix schenckii
exudates from animals other than cats
should be examined using
immunofluorescence
Because Sporothrix schenckii
is a dimorphic fungi, it grows as mold at room temp and like yeast at 37C.
What does it look like at room temp?
What do you see at 37C?
At room temp- branching septate hyphae and pyriform microconidia
At 37C- budding and pleiomorphic, cigar shaped
**Cutaneous forms **of *Sporothrix schenckii *is treated using
Inorganic iodides
Disseminated form of Sporothrix schenckii
is treated using
Itraconazole
Amphotericin B
Flucytosine