Test 1 Studying Flashcards
4 types of glial cells
Oligodendrocytes, Schwann cells, Astrocytes, and microglial cells.
Oligodendrocytes
Forms myelin in the CNS
Schwann Cells
Forms myelin in the PNS
Astrocytes
Numerous processes including forming tough outer membranes of the brain.
Microglial Cells
Primary job is contain and cleaning up sites of injury. Remove cellular debris.
Multipolar neurons
Most common. Many dendrites –> a single axon
Bipolar neurons
Common in sensory systems. Single dendrite –> single axon
Unipolar neurons
Single branch(axon) that leaves cell body then extends in two directions. One is input zone(dendrites) and the other end is output zone(terminals).
Differentiate between grey and white matter
Grey matter: mostly receives and processes info
White matter: mostly transmits info
Brainstem parts
Midbrain, pons, medulla
Midbrain parts
Tectum: Superior colliculi
Inferior colliculi
Motor: Substantia Nigra
Other: Reticular formation
Periaqueductal gray
Cervical
Neck (8 segments)
Thoracic
Trunk (12 segments)
Lumbar
Lower back (5 segments)
Sacral
Pelvic (5 segments)
Coccygeal
Bottom (1 segment)
Different levels of analysis
Social>Organ>Neural Systems> Brain Region>Circuit>Cellular>Synaptic>Molecular
Resting potential
(-70mV) Cells interior is more negative
Depolarization
(-55mV) Positive Na ions enter the cell through Na channels to make it more positive up to +30mV
Repolarization
Potassium channels open slowly allowing potassium to flow out bringing the voltage back to zero.
Why does myelin speed up conduction?
Saltatory conduction lets action potentials jump between myelin because it resists the flow of ions
Influences on action potential conduction velocity
Larger axon diameter=spread faster
Excitatory postsynaptic potentials (EPSP)
Increase the probability that a postsynaptic neuron will fire an action potential
Inhibitory postsynaptic potentials (IPSP)
Decreases the probability that a postsynaptic neuron will fire an action potential
Spatial summation
Summing of all potentials that reach the axon hillock, if the sum reaches the threshold we get an action potential
Temporal summation
Summing of all potential but based on time of arrival. The closer together the greater their impact and chance of making an action potential
Sequence of chemical transmission between two neurons
- Action potential arrives at presynaptic neuron
- Voltage gated Ca channels in the terminal open and Ca enters
- Ca causes synaptic vesicles to fuse and dump neurotransmitters into synaptic cleft
- Transmitters bind to postsynaptic receptor molecules causing ion channels to open and leading to an EPSP or IPSP
- EPSP or IPSP spreads toward postsynaptic axon hillock, if threshold is reached then we get action potential
- Synaptic transmission is rapidly stopped
- Transmitter may activate presynaptic receipts that decrease transmitter release
Tonic-clonic seizures
Abnormal EEG activity all over