Teratogens

Question 0

It has the greatest effect on cells undergoing what kind of development? (cells are dividing the most) ex.brain

Answer 0

Rapid development

Question 1

A substance that negatively affects normal fetal growth and development

Answer 1

Teratogen

Question 2

Organogenesis occurs when?

Answer 2

Prior to 8 weeks (2-8 weeks)

Question 3

What percentage of medications are linked to birth defects?

Answer 3

10%

Question 4

What percentage of women use at least one medication?

Answer 4

60%

Question 5

This medication presents as a risk for spontaneous abortion and congenital anomalies

Answer 5

Accutane

Question 6

This medication presents as odotoxic (ears)

Answer 6

Mycins (gentamycin)

Question 7

This medication increases risks of neural tube defects, cleft palate, IVGR (intrauterine growth restriction), and cognitive abnormalities

Answer 7

Anticonvulsants - valproic acid and carbamezapine

Question 8

This medication can prolong labor or inhibit labor; inhibits prostaglandin synthesis which can cause premature ductus arteriosis constriction (valve that allows fetal circulation). Do not use late in pregnancy and after 28 weeks do not use AT ALL.

Answer 8

Salycilates (NSAIDs)

Question 9

This medication presents as a risk for yellow teeth and depresses skeleton growth of the fetus

Answer 9

Tetracycline (doxycycline)

Question 10

This medication has an increased risk of birth defects, IUGR, fetal death (3x more like to have birth defects)

Answer 10

ACE inhibitors

Question 11

This medication has a risk for spontaneous abortion, fetal demise, and newborn hemorrhage, CNS defects because it crosses the placenta barrier.

Answer 11

Warfarin (Coumadin)

Question 12

All of these are contraindicated. Recommended to use inactivated injections.

Answer 12

Love virus vaccines

Question 13

The FDA classification system has how many categories?

Answer 13

5 (ABCDX)

Question 14

Adequate well controlled studies have failed to show fetal risk

Answer 14

Category A

Question 15

Animal studies have failed to show fetal risk

Answer 15

Category B

Question 16

Animal studies show fetal risk; benefits may warrant use

Answer 16

Category C

Question 17

Evidence of human fetal risk; benefits may warrant use

Answer 17

Category D

Question 18

Studies have shown fetal abnormalities

Answer 18

Category X

Question 19

What is considered a safe amount of caffeine daily?

Answer 19

300mg

Question 20

The usage of this drug causes decreased uterine blood flow, and decreased oxygen during pregnancy.

Answer 20

Smoking

Question 21

This is type of smoking is also harmful.

Answer 21

Secondhand smoke

Question 22

The risks associated with smoking cause low birth weight and IUGR, preterm delivery, fetal death, SIDS, asthma, childhood cancer, learning disabilities, infant ear and respiratory infections due to what?

Answer 22

Lack of oxygen
Chemicals
Vasoconstriction

Question 23

The most common teratogen cause of mental retardation

Answer 23

Alcohol use and abuse

Question 24

Alcohol passes to the fetus via the placenta within

Answer 24

Seconds

Question 25

The risk for FAS are higher in what ethnic groups?

Answer 25

Alaskans, American Indians, and African Americans

Question 26

All categories of prenatal alcohol exposure are termed:

Answer 26

Fetal alcohol syndrome disorder