teratogenic meds Flashcards

1
Q

ACE inhibitors effect on fetus

A

renal damage

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2
Q

akylating agents

A

absence of digits

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3
Q

aminoglycosides

A

CN VIII toxicity a mean guy hit the baby in the ear

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4
Q

carbamazepine

A

neural tube defects, craniofacial defects, fingernail hypoplasia, developmental delay, IUGR

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5
Q

DES

A

mullerian anomalies, vaginal clear cell adenocarcinoma

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6
Q

lithium

A

Ebstein anomaly (atrialied right ventricle)

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7
Q

methimazole

A

aplasia cutis congenita

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8
Q

phenytoin

A

fetal hydantoin syndrome: microcephaly, dysmorphic craniofacial features, hypoplastic nails and distal phalanges, cardiac defects, IUGR, intellectual disability

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9
Q

tetracyclines

A

discolored teeth teethocyclines

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10
Q

thalidomide

A

limb defects limb defects with tha-limb-domide

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11
Q

valproate

A

inhibits folate; neural tube defects

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12
Q

warfarin

A

bone deformities, fetal hemorrhage, abortion, optho abnormalities

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