cytokines Flashcards

1
Q

endogenous pyrogen, causes fever, acute inflammation

A

IL-1

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2
Q

endogenous pyrogen, secreted by TH2, causes fever and stimulates production of acute phase proteins

A

IL-6

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3
Q

chemotactic factor for neutrophils

A

IL-8

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4
Q

induces differentiation of T cells into TH1 cells. activates NK cells

A

IL-12

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5
Q

mediates septic shock

A

TNF alpha

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6
Q

stimulates growth of helper, cytotoxic, regulatory T cells

A

IL-2

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7
Q

growth and differentiation of bone marrow stem cells

A

IL-3

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8
Q

activates NK cells to kill virus infected cells, incr MHC expression and Ag presentation

A

IFN-gamma

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9
Q

induces differentiation into TH2 cells, promotes B cell growth, enhances class switching to IgE and IgG

A

IL-4

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10
Q

enhances class switching to IgA, stimulates growth of eosinophils

A

IL-5

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11
Q

inhibits actions of activated T cells and TH1

A

IL-10

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