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Farma > Terapias Dirigidas > Flashcards

Terapias Dirigidas Flashcards

1
Q

Mecanismo de acción Imatinib

A

Inhibidores de cinasa de tirosina de Bcr-Abl
Inhibe la proliferación celular e induce a apoptosis en Leucemia mieloide crónica con cromosoma Philadelphia

Inhibe cinasas de tirosina PDGF, SCF, c-Kit —> apoptosis células Tumores Estroma Gastrointestinal

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2
Q

Mecanismo de acción Bortezomib

A

Inhibidor del proteasoma en la unidad 26S

Detención ciclo celular y apoptosis

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3
Q

Mecanismo de acción Rituximab

A

Anticuerpos monoclonales

Unión al antígeno CD20 de los linfos B —> activación citotoxicidad células B por el complemento

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4
Q

Agentes anti HER 2

A

Trastuzumab
Pertuzumab
Lapatinib

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5
Q

Mecanismo de acción Bevacizumab

A

Anticuerpo monoclonal inhibidor de VEGF

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6
Q

Agentes Anti TNF

A

Infliximab, Adalimumab, Etanercept

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7
Q

Mecanismo de acción Omalizumab

A

Anti IgE

Anticuerpo monoclonal IgG dirigido a IgE

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Farma (29 decks)

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