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Farma > Antiemeticos Y Agentes Con Efecto Sobre La Motilidad > Flashcards

Antiemeticos Y Agentes Con Efecto Sobre La Motilidad Flashcards

1
Q

Mecanismo de acción de Ondansetron y palonosetron

A

Antagonista receptor 3 de serotonina (5HT3)

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2
Q

Mecanismo de acción de Aprepitant y Fosaprepitant

A

Antiemeticos

Inhibición receptor sustancia P/neurocinina 1 (NK1) en SNC

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3
Q

Mecanismo de acción metoclopramida

A

Agonista receptor 5HT4
Antagonista 5HT3
Sensibilizacion receptores muscarinicos del músculo liso
Antagonista receptor D2 dopamina
Aumenta contractilidad en el tracto digestivo superior

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4
Q

Toxicidad metoclopramida

A

Efectos extrapiramidales

Galactorrea

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5
Q

Mecanismo de acción Cisaprida

A

Motilidad intestinal
Agonista 5HT4
Estimula actividad adenilciclasa
Antagonista 5HT3

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6
Q

Toxicidad cisaprida

A

Arritmias : Taquicardia, FV y torsade pointes

Contraindicada en cardiopatías

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7
Q

Mecanismo de acción Loperamida

A

Opioide
Disminución tránsito intestinal
Incremento del tono del esfínter anal
Actividad antisecretora contra toxinas bacterianas

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8
Q

Toxicidad loperamida

A

Estreñimiento
Depresión SNC
Ileo paralitico

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Farma (29 decks)

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