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Farma > AINES > Flashcards

AINES Flashcards

1
Q

AINES mecanismo de acción

A

Inhibición de isoformas 1 y 2 de la ciclooxigenasa —> inhibición síntesis prostaglandinas inducida por citocinas

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2
Q

Toxicidad AINES

A

Dispepsia, úlcera y hemorragia gastrica
Disminución perfusion renal
Asma
Lesión hepatocelular aguda —> paracetamol
Tinnitus y mareos, Sx Reye —> salicilatos

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3
Q

Inhibidores selectivos de la ciclooxigenasa 2

A

Celecoxib
Lumiracoxib
Parecoxib
Etoricoxib

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4
Q

Mecanismo de acción Celecoxib, Lumiracoxib, Parecoxib, Etoricoxib

A

Inhibición isoforma 2 ciclooxigenasa

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5
Q

Toxicidad celecoxib e inhibidores selectivos ciclooxigenasa

A

IAM
ACV
Edema
HTA

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