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Farma > Antidepresivos > Flashcards

Antidepresivos Flashcards

1
Q

Antidepresivos triciclicos

A

Imipramina y amitriptilina

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2
Q

Mecanismo de acción Imipramina y Amitriptilina

A

Antidepresivos triciclicos

Inhibición recaptura de neuro transmisores (noradrenalina y serotonina)

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3
Q

Toxicidad Antidepresivos triciclicos (imipranina y amitriptilina)

A 
Sedación 
Temblor
Insomnio 
Visión borrosa
Estreñimiento
Hipotension ortostatica
Agravamiento psicosis 
Sx deprivacion
Convulsiones
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4
Q

Antidepresivo de segunda generación

A

Bupropion

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5
Q

Mecanismo de acción bupropion

A

Antidepresivo

Vías dopaminergicas y noradrenergicas

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6
Q

Toxicidad bupropion

A 
Mareo
Xerostomia
Sudoración 
Temblor
Psicosis
Convulsión
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7
Q

Antidepresivos tercera generación

A

Mirtazapina
Venlafaxina
Duloxetina

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8
Q

Mecanismo de acción Mirtazapina

A

Antidepresivo

Liberación norepinefrina y serotonina

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9
Q

Mecanismo de acción Venlafaxina

A

Antidepresivo

Inhibe recaptura de norepinefrina y serotonina, dopamina

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10
Q

Mecanismo de acción Duloxetina

A

Antidepresivo

inhibe recaptura de serotonina y norepinefrina

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11
Q

Toxicidad Venlafaxina

A

Hipertensión

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12
Q

Toxicidad Duloxetina

A

Insomnio e hiporexia

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13
Q

Fármacos ISRS

A 
Fluoxetine
Proxetina 
Sertralina
Fluvoxamina
Citalopram
Escitalopram
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14
Q 
Mecanismo de acción: Fluoxetine
Proxetina 
Sertralina
Fluvoxamina
Citalopram
Escitalopram
A

ISRS

afinidad receptores adrenergicos A1, histaminergicos y colinergicos

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15
Q

Toxicidad ISRS

A

Ansiedad, insomnio
Gastrointestinales
Disminución libido, disfunción sexual
Teratogenicidad Paroxetina

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16
Q

Fármaco antidepresivo inhibidor de la monoaminooxidasa

A

Selegilina

17
Q

Mecanismo de acción selegilina

A

Fármaco antidepresivo inhibidor de la monoaminooxidasa A y B

18
Q

Toxicidad selegilina

A

Sx serotoninergico al interactuar con alimentos con tiramina

Cafalea, somnolencia, xerostomia, ganancia ponderal, hipotension postural

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