Agentes Usados En La Migraña Flashcards

1
Q

Fármacos triptanos

A

Sumatriptan
Zolmitriptan
Almotriptan
Eletriptan

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2
Q

Mecanismo de acción triptanos

A

Migraña
Agonistas receptor 5HT serotonina

Construcción vasos intracraneales y anastomosis arteriovenosas—> restaurando el flujo sanguíneo cerebral

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3
Q

Toxicidad sumatriptan

A

Toxindrome serotoninergico si se combina con antidepresivos

Eventos cardiacos: vaso espasmo coronario, arritmias, IAM

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4
Q

Contraindicación triptanos

A
E coronaría isquemica o vasoespastica
Ataque isquemico transitorio 
ECV 
E isquemicas intestinales 
HTA
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5
Q

Mecanismo de acción Ergotamina

A

Migraña

Agonismo receptor 5HT serotonina

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6
Q

Toxicidad Ergotamina

A
Fibrosis inflamatoria (pleuropulmonar, coronaria, endocardio) 
Retrocede al retirar el fármaco
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