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Behavioral Health > TCAs > Flashcards

TCAs Flashcards

1
Q

amitriptyline

A

elavil

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2
Q

nortriptyline

A

pamelor

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3
Q

desipramine

A

norpramin

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4
Q

doxepin

A

silenor

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5
Q

MOA of TCAs

A

inhibits reuptake of serotonin/norepinephrine AND blocks action of acetylcholine (and histamine)

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6
Q

metabolism of TCAs

A

liver

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7
Q

indications of TCAs

A

MDD, dysthymia, depression phase of BPD, OCD, bedwetting, migraines, chronic pain, MANY off labels

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8
Q

are side effects of TCAs dose related?

A

YES

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9
Q

is any screening needed before putting a patient on a TCA?

A

EKG if over 40 (risk of QT prolongation)

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10
Q

anticholinergic side effects of TCAs?

A

sedation, dizziness, constipation, blurred vision, urinary retention, dry mouth, heat intolerance, tachycardia, exacerbation of glaucoma

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11
Q

alpha-1 blocker side effects of TCAs?

A

orthostatic hypotension

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12
Q

which TCA has the least orthostatic hypotension?

A

pamelor

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13
Q

sexual dysfunction side effects of TCAs?

A

erectile/ejaculatory in males

anorgasmia in females

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14
Q

is overdose of TCAs fatal?

A

YES! usually from QT prolongation leading to an arrhythmia and hypotension, also agitation, delirium, seizures, coma

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15
Q

is dialysis effective in a TCA overdose?

A

NOPE! it’s lipopholic

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16
Q

treatment of TCA overdose

A

gastic lavage, activated charcol, cardiac monitor and supportive therapy (sodium bicarb)

17
Q

Clomipramine

A

Anafranil

18
Q

Which TCA is the least sedating?

A

Norpramin

19
Q

Which TCA has the least anticholinergic side effects?

A

Norpramin

20
Q

What is a special use of anafranil?

A

OCD

21
Q

Which TCA is most serotonin specific?

A

Anafranil

22
Q

Major complications of TCAs?

A

Convulsions, Coma, Cardiotoxicity

Behavioral Health (15 decks)

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