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Behavioral Health > Mood Stabilizers > Flashcards

Mood Stabilizers Flashcards

1
Q

lithium

A

eskalith

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2
Q

MOA of lithium

A

unknown

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3
Q

indication of lithium

A

acute mania and maintenance of bipolar disorder (considered 1st line)

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4
Q

side effects of lithium

A

GI distress, weight gain, fine tremor, cognitive impairment

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5
Q

is lithium toxic or fatal in overdose?

A

it can be - n/v/d, corse tremor, ataxia, sludder speech, confusion, arrhythmia

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6
Q

long term side effects of lithium

A

kidney: concentrating defects, nephrogenic diabetes insipidus
hypothyroidism, goiter
cardiac arrhythmia due to sinus node dysfunction

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7
Q

are baseline labs needed before placing a patient on lithium?

A

CBC, BMP, EKG, TSH/T4, bHCG

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8
Q

do lithium levels need to be monitored?

A

YES, every 2-6 months along with TSH and kidney function

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9
Q

pregnancy category

A

D -> cardiac anomalies

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10
Q

valproate

A

depakene, depakote

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11
Q

MOA valproate

A

reason for therapeutic effect not understood

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12
Q

indication for valproate

A

actue mania and maintenance for BPD, schizoaffective d/o, schizophrenia, restrictive depressive d/o, impulse control d/o, borderline PD, behavioral disturbances associated with developmental disability

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13
Q

black box warnings for valproate

A
  1. hepatotoxicity - usually within the first 6 months, mostly
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14
Q

common side effects for valproate

A

GI upset, weight gain, sedation, tremor, hair loss

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15
Q

can valproate be combined with lithium?

A

YES

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16
Q

can valproate be combined with lamictal?

A

NO - SJS

17
Q

baseline screening for valproate?

A

YES LFTs, CBC, platelet, bHCG

18
Q

monitoring for valproate?

A

alproic acid levels, LFTs after 1 month then every 6-24 months

19
Q

lamotrigine

A

lamictil

20
Q

MOA of lamictil

A

blocks Na channels in the brain related to neuron firing which diminishes the buildup of glutamate in the CSF, modest inhibition of serotonin reuptake

21
Q

indications for lamictil

A

maintenance of BPD (NOT FDA approved for acute)

22
Q

what happens if you increase the dose of lamictil too quickly?

A

SJS

23
Q

side effects of lamictil

A

mild - dizzy, HA, blurred vision, nausea, back/joint pain, cognitive impairment often self reported

24
Q

labs for lamictil?

A

NOPE, no baseline or monitoring

25
Q

How is lithium secreted?

A

Kidney

26
Q

Onset of action of lithium

A

5-7 days

27
Q

Major drawback of lithium

A

High incidence of side effects and a very narrow therapeutic index

28
Q

Carbamazepine

A

Tegretol

29
Q

What type of drug is Tegretol?

A

Anticonvulsant

30
Q

Use of Tegretol

A

Mixed episodes and rapid cycling bipolar disorder

Also used in management of trigrminal neuralgia

31
Q

MOA of Tegretol

A

Blocks Na channels and inhibits action potentials

32
Q

Onset of Tegretol

A

5-7 days

33
Q

Side effects of Tegretol

A

Rash, drowsiness, ataxia, slurred speech, leukopenia, hyponatremia, aplastic anemia, agranulocytosis and elevation of liver enzymes

34
Q

Can Tegretol be given in pregnancy?

A

No! It’s teratogenic

35
Q

What labs should be monitored if a patient is on Tegretol?

A

CBC and LFTs

Behavioral Health (15 decks)

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