Neurotransmitters Flashcards

1
Q

what neurotransmitter binds to dopaminergic receptors?

A

dopamine

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2
Q

what neurotransmitter binds to adrenergic receptors?

A

norepinephrine and epinephrine

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3
Q

what neurotransmitter binds to noradrenergic receptors?

A

norepinephrine

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4
Q

what neurotransmitter binds to serotonergic receptors?

A

serotonin

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5
Q

what neurotransmitter binds to cholinergic receptors?

A

acetylcholine

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6
Q

two types of cholinergic receptors

A

muscarinic and nicotinic

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7
Q

abbreviation for serotonin

A

5-HT (5-hydroxytryptamine)

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8
Q

components of serotonin

A

tryptophan + tryptophan hyxroxylase

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9
Q

where is serotonin found?

A

majority is in the GI tract, but some in the brain

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10
Q

do serum levels of serotonin correlate with brain serotonin levels?

A

NO serum serotonin CANNOT cross the BBB

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11
Q

specific location of serotonin in the brainstem

A

raphe nuclei

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12
Q

some roles of serotonin

A

sleep, mood, sexual desire, sexual function, appetite, memory, learning, temperature regulation and social behavior

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13
Q

what type of neurotransmitter is dopamine?

A

catacholamine

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14
Q

what type of neurotransmitter is norepinephrine?

A

catacholamine

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15
Q

where are dopamine and norpeinephrine derived?

A

tyrosine from diet

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16
Q

what happens when tyrosine enters dopaminergic neurons?

A

chemical transformation

17
Q

steps of tyrosine to dopamine and norepinephrine conversion

A
  1. tyrosine + tyrosine hydroxylase = L-DOPA
  2. L-DOPA + L-amino acid decarboxylase = dopamine
  3. dopamine + dopamine beta-hydroxylase = norepinephrine
18
Q

how many dopaminergic neurons are there compared to adrenergic?

A

MANY, MANY more

19
Q

primary locations of dopaminergic neurons

A
  • nigrostriatal: movement control (think parkinsons)
  • mesolimbic: reward effects of pleasure
  • mesocortical: planning and problem solving
20
Q

rols of norepinephrine

A

attention and responding reactions, fight or flight response, arousal and alertness, memory

21
Q

what degrades norepinephrine that is in the synapse?

A

monoamine oxidase (MAO)

22
Q

where is norepinephrine released?

A

pons, medulla and some of the thalamus (projections to most areas of the brain)