Misc. Drugs Flashcards

1
Q

flumazenil

A

romazicon

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2
Q

indication for romazicon

A

benzo overdose

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3
Q

MOA of romazicon

A

block/reverse CNS effects of benzos but NOT other sedatives like ETOH or barbituates

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4
Q

side effect of romazicon

A

n/v, dizziness, agitation and emotional lability

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5
Q

issue with romazicon

A

may initiate seizures

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6
Q

half life of romazicon

A

VERY short so sedation will often return

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7
Q

buspirone

A

buspar

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8
Q

MOA of buspar

A

serotonin 1A agonist

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9
Q

indication for buspar

A

GAD, augment tx for depression and OCD

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10
Q

benefit of buspar over benzos

A

lacks sedation and dependence

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11
Q

is there a withdrawal from buspar?

A

NOPE

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12
Q

what happens if a patient has taken benzos before and now is on buspar?

A

reduced effectiveness

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13
Q

time to symptom relief with buspar?

A

2-4 weeks

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14
Q

how many times is buspar dosed a day?

A

3 - short half life

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15
Q

hydroxyzine

A

atarax

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16
Q

MOA of atarax

A

antihistamine and anixolytic

17
Q

indication for atarax

A

anxiety in the short term and sometimes to augment sedative effects of antipsychotics in acute agitation

18
Q

is ther dependence associated with atarax?

19
Q

limit of atarax?

A

anticholinergic side effefcts

20
Q

ramelteon

21
Q

MOA of rozeram

A

melatonin agonist

22
Q

indication for rozeram

A

onset insomnia

23
Q

who cannot get rozeram

A

liver insufficient patients

24
Q

diphenhydramine

25
indication of benadryl
little evidence that it improves insomnia
26
side effects of benadryl
anticholinergic and sedation the next day (long half life)
27
modanfinil
provigil
28
MOA of provigil
unknown, but probably increases domaminergic signaling
29
indications for provigil
narcolepsy and those who need to maintain wakefulness
30
comparison of provigil to amphetamines
equal effect on wakefullness, but provigil has less risk of excessive activation