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Behavioral Health > SNRIs > Flashcards

SNRIs Flashcards

1
Q

desvenlaxafine

A

pristiq

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2
Q

venlaxafine

A

effexor

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3
Q

duloxetine

A

cymbalta

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4
Q

minacipran

A

savella

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5
Q

MOA of SNRIs

A

block presynaptic serotonin and norepinephrine transporter proteins which results in inhibited reuptake of transmitters leading to an increased stimulation of the post-synaptic receptors

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6
Q

are SNRIs more potent on serotonin or norepinephrine?

A

serotonin

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7
Q

do SNRIs have an effect on other receptors?

A

NOPE, no effect on histamine, cholinergic, dopaminergic or adrenergic

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8
Q

indication for pristiq

A

MDD

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9
Q

indication for effexor

A

MDD, anxiety (GAD, SAD, panic) and ADHD

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10
Q

indication for cymbalta

A

MDD

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11
Q

indication for savella

A

ONLY fibromyalgia

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12
Q

side effects of the SNRIs

A

sexual dysfunction, insomnia, GI effects

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13
Q

what side effects are lacking for SNRIs?

A

anitcholinergic effects, weight gain, orthostatic hypotension

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14
Q

why is effexor nicknamed “side effexor”?

A

HTN, nausea, somnolence, dizziness, constipation, anorexia, blurred vision

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15
Q

can SNRIs be given with an MAOI?

A

NO -> serotonin syndrome (MUST wait at least 2 weeks)

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16
Q

is effexor good in severly depressed patients?

A

surprisingly, YES! it works faster than usual antidepressatns

17
Q

Who should not be given Effexor?

A

Patients with untreated or labile BPs - can make HYN worse

18
Q

Potential withdrawal symptoms from Effexor

A

Flulike symptoms can be seen with 1-3 missed doses, not life threatening but very uncomfortable

19
Q

Who should not be given Effexor?

A

Patients with untreated or labile BPs - can make HYN worse

20
Q

Potential withdrawal symptoms from Effexor

A

Flulike symptoms can be seen with 1-3 missed doses, not life threatening but very uncomfortable

Behavioral Health (15 decks)

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