Taste and smell Flashcards

1
Q

where are taste buds found

A

tongue, palate, tonsillar pillars, epiglottis and proximal oesophagus

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2
Q

where are circumvallate papillae found

A

posterior of tongue in a v shape

taste buds are found on these papillae

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3
Q

where are fungiform papillae found

A

anterior surface of the tongue

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4
Q

where are foliate papillae found

A

lateral margins

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5
Q

where are taste buds found on the papillae

A

embedded on the sides of the papillae

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6
Q

what chemicals can be tasted by taste buds

A
potassium
sodium 
chloride
adenosine
inosine
sweet 
bitter
glutamate
H+
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7
Q

what causes sour taste

A

H+

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8
Q

what causes salty taste

A

Na and K ions

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9
Q

what causes sweet taste

A

sugar and other similar chemicals - glycols, alcohols, ketones and others

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10
Q

what causes bitter tastts

A

many chemicals including alkaloids found in toxic plants

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11
Q

what causes umami taste

A

L glutamate

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12
Q

how do taste buds work

A

contain receptors which depolarise taste cells by either an ionotropic or metabotropic pathway

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13
Q

what are the relative taste thresholds for various tastes

A

bitter has the lowest threshold as it most commonly associated with dangerous substances so sensitivity must be high

sour is next lowest
then sweet and then salty

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14
Q

what is the taste pathway to the cortex

A

solitary nucleus, then thalamus, then insula and anterior operculum

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15
Q

where do the limbic components of taste go

A

via the thalamus

can activate brainstem nuclei for salivation or vomiting

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16
Q

where does pain from spicy food travel

A

posterior parts of tongue to cn 5

17
Q

what are the components of the olfactory system

A

olfactory epithelium
receptor cells (bipolar neurons)
axons that project to the olfactory bulb
neuronal tract to multiple olfactory destinations in the brain

18
Q

where is the olfactory epithelium

A

high in the nasal cavity below the cribriform plate

19
Q

what types of neurones detect smell

A

bipolar

20
Q

where is the olfactory bulb

A

just above and anterior to the cribriform plate

21
Q

what gland secretes mucus into the olfactory epithelium

A

bowman’s gland

22
Q

what strucuture detects odorants

A

olfactory cillia formed from the olfactory knob

23
Q

describe activation of the odorant receptor

A

an molecule binds to the receptor of the primary olfactory neurone

the activated receptor activates a G protein which stimulates adenylyl cyclase to convert ATP to cAMP

cAMP activates a cation channel, making it permeable to Na +and Ca2+, thus depolarising the cell

24
Q

what is the frequency of action potentials proportional to

A

log concentration of odorant

25
Q

how many genes are there for odorant receptors

A

over 300

each neuron expresses just one gene per neuron

26
Q

what are the 7 types of odour

A
  1. Camphoraceous
  2. Musky
  3. Floral
  4. Pepperminty
  5. Ethereal
  6. Pungent
  7. Putrid
27
Q

what is the function of the medial olfactory pathway

A

feeds into limbic system and encodes the emotional aspect olfaction and memory (ancient part)

28
Q

what is the function of the lateral olfactory pathway

A

feeds to less ancient parts of brain such as the pyriform cortex in the temporal lobe

involved in likes and dislikes as well as visceral reactions via brainstem, does not go via the thalamus

29
Q

what is the more recent olfactory pathway

A

thalamus
to orbitofrontal cortex

involved in conscious discernment of odour

30
Q

where does the olfactory tract project to

A

olfactory cortex

hypothalamus, amygdala, limbic system, hippocampus

31
Q

what reflexes can olfaction cause

A

salivation, gastric secretions, sneezing

gagging, vomiting