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Pharmaceutics II > Tablets > Flashcards

Tablets Flashcards

1
Q

Define tablets

A
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2
Q

Tablets are prepared with the aid of what

A

Suitable pharmaceutical excipients

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3
Q

What are the characteristics of the tablets

A
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4
Q

How are tablets used ?

A
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5
Q

What are the advantages of tablets

A

Convenient and safe way for drug administration
Chemical, physical, and microbiological stability
Accurate dosing
Convenient to handle and can be prepared in a versatile way
Cheap to produce with robust and quality-controlled production

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6
Q

What are the disadvantages of the tablets

A
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7
Q

What are the types of tablets

A

Compressed tablets
Multiply compressed tablets
Sugar coating tablets
Film-coated tablets
Gelatin-coated tablets
Enteric-coated tablets
Buccal and sublingual tablets
Lozenges
Chewable tablets
Effervescent tablets
Vaginal tablets
Modified release tablets

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8
Q

Define compressed tablets

A

Round, oblong or unique in shape
Thick or thin
Large or small in diameter
Flat or convex

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9
Q

Explain multiply compressed tablets

A
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10
Q

Plain sugar coating tablets

A

Compressed tablets may be coated with a colored or uncolored sugar layer

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11
Q

Explain film-coated tablets

A

Compressed tablets coated with a thin layer of a polymer capable of forming a skin like film

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12
Q

Explain gelatin-coated tablet

A
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13
Q

Explain enteric-coated tablets

A
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14
Q

Explain buccal and sublingual tablets

A
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15
Q

Explain lozenges

A
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16
Q

Explain chewable tablets

A
17
Q

Explain effervescent tablets

A
18
Q

Explain vaginal tablets

A
19
Q

What are the types of tablet excipients

A

Diluents or fillers
Binders or adhesives
Disintegrating agents
Anti adherence, glidants, lubricants
Miscellaneous adjuncts such as colorants and flavorants

20
Q

What is the need of diluents or fillers

A

They add the necessary bulk to formulation to prepare tablets of the desired size and a practical size for compression

21
Q

What are the examples of diluents or fillers

A

Lactose, di calcium phosphate, microcrystalline cellulose(Avicel)

22
Q

Microcrystalline cellulose (Avicel) is used as what

A

An excipient in direct compression method and in wet granulation method

23
Q

Why are binders or adhesives used

A

Promote adhesion of the particles of the formulation, allowing a granulation to be prepared and maintaining the integrity of the final tablet

They are added to impart cohesive qualities to the powdered material to ensure the tablet remaining intact after compression

24
Q

Give example of binders or adhesives

A

Gums, acacia

25
Q

Why are disintegrating agents used ?

A

Promote breakup of the tablets after administration to smaller particles for ready drug availability
They are added to facilitate tablet break up or fragmentation in the GIT, after administration

26
Q

Give example of disintegrating agent

A

Corn starch

27
Q

Why are anti-adherence, glidants and lubricants added

A
28
Q

What are the examples of anti-adherents glidants and lubricants

A

Magnesium stearate
Calcium stearate

29
Q

Why are miscellaneous adjuncts used

A
30
Q

What is an example for miscellaneous adjuncts

A

Natural - mannitol and lactose
Artificial - saccharin and aspartame

31
Q

What are the general methods of tablet preparation

A

Direct compression
Dry-granulation
Wet-granulation

Pharmaceutics II (25 decks)

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