Quality Control Of Tablets Flashcards
What are the quality control test of tablets
Explain the color as the organoleptic property of the tablet
Explain the odor as the organoleptic property of the tablet
Explain the taste as the organoleptic property of the tablet
List the official quality control test
Weight variation test
Disintegration test
Dissolution test
Drug content
Why should the weight of tablets routinely measured ?
To help ensure that the tablet contains the proper amount of drug
Explain the in practice weight variation test
What is the limit provided by the USP for the weight variation
Explain the disintegration test
What is the disintegration test essential for ?
What is the disintegration time for uncoated USP tablets the lowest and maximum
5 minutes
30 minutes maximum
What is the disintegration for enteric coated tablets
What is the limit for disintegration test
What does the dissolution test (in vitro drug release) measure
What equipment is used for the dissolution / in vitro drug release test
Describe the method of dissolution test
The potency of tablet is expressed in terms of what
What is the potency range of digitoxin
What is the potency for large - dose drugs
What do the potency analytical methods require
When can weight be used as a potency indicator
What are the three factors that can directly contribute to content uniformity problems in tablets
Define tablet hardness
What is done to perform the hardness test
What is the importance of the hardness test
What is the disadvantage of tablets that tent to powder
Explain the friability test
What is the limit for tablet thickness
Why should thickness be controlled
What are the characteristics of ideal tablets
