Drug Dissolution Flashcards
1
Q
Define dissolution
A
Involves the replacement of crystal molecules by solvent molecules
The dissolution of a solid in a liquid may be regarded as being composed of two consecutive stages
2
Q
What is the first stage of drug dissolution
A
3
Q
What is the second stage in drug dissolution
A
4
Q
The process of the removal of drug maleate from a solid and their replacement by solvent molecules is determined by what
A
The relative affinity of the various molecules involved
5
Q
What must be overcomed for drug dissolution
A
6
Q
How to know the rate of dissolution
A
7
Q
What is the Noyes-Whitney equation
A
8
Q
What are the factors affecting dissolution rate
A