Creams And Gels Flashcards

1
Q

Define cream

A
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2
Q

The composition of a cream typically includes what three main components?

A

Water phase
Oil phase
Emulsifying agent

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3
Q

What is meant by water phase

A
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4
Q

What is meant by oil phase

A
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5
Q

What is meant by emulsifying agent

A
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6
Q

What are other additives added to cream?

A

Preservatives
Thickeners
Humectants
Fragrances
Colorants

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7
Q

What are the purposes of creams

A

Moisturizing
Protecting
Soothing
Delivering active ingredients to treat various skin conditions

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8
Q

What are the examples of active ingredients that the creams can be formulated with

A

Anti-inflammatory agents
Antimicrobial agents
Corticosteroids
Anti-fungal agents
Local anesthetics

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9
Q

What are creams designed for

A

For external use only and should not be ingested or used on open wounds without medical supervision

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10
Q

Many patients and physicians prefer creams to ointments why

A

Because they are easier to spread and remove

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11
Q

What do pharmaceutical manufacturers do to satisfy the preferences of the patients and physicians

A

They manufacture topical preparations of a drug in both cream and ointment bases

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12
Q

Define cosmeceuticals

A
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13
Q

Define gels

A

Semi-solid system that consists of a network of solid particles dispersed in a liquid phase

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14
Q

Gels are designed to provide what

A
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15
Q

What are the gels main features

A

Gel matrix
Liquid phase
API
Penetration enhancers
Stabilizers and preservatives
Rheology modifiers

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16
Q

Explain the gel matrix feature

A
17
Q

Explain the liquid phase feature

A
18
Q

Explain the API feature

A
19
Q

Explain the penetration enhancers feature

A
20
Q

Explain the stabilizers and preservatives feature

A
21
Q

Explain the rheology feature

A
22
Q

What are advantages of gels ?

A

Localized drug delivery
Enhanced drug retention
Non-greasy and non-staining
Versatile formulation
Ease of administration

23
Q

Explain the localized drug delivery advantage of gel

A
24
Q

Explain the enhanced drug retention advantage of the gel

A
25
Q

Explain the non-greasy and non+staining advantage of gel

A
26
Q

Explain the versatile formulation advantage of gel

A
27
Q

Explain the ease of administration advantage of gel

A
28
Q

Define thixotropy

A
29
Q

What does the mechanism of thixotropy include ?

A

Network breakdown
Network reformation

30
Q

Explain the network breakdown

A
31
Q

Explain the network reformation

A
32
Q

What is the application of thixotropy in pharmaceuticals ?

A