T2 - Pulmonary System (Josh) Flashcards
Which Bronchus will likely be where a kid gets something stuck?
Right Bronchus
***The right main bronchus is wider, shorter, and more vertical than the left main bronchus.
What are the 3 steps of Gas Exchange?
Step 1 = Ventilation
Step 2 = Respiration
Step 3 = Transport of Gases into the Circulation
Gas Exchange:
The process of moving air between atmosphere and the lung alveoli and distributing air within the lungs to maintain appropriate concentrations of Oxygen and Carbon Dioxide in the alveoli.
Ventilation
***exchange between AIR and LUNG
Gas Exchange:
The process by which alveolar air gasses are moved across the alveolar-capillary membrane to the pulmonary capillary bed.
Respiration
***exchange of O2 and CO2 at ALVEOLAR LEVEL
Which type of Alveoli are squamous and used for gas exchange?
Type I
Which type of Alveoli are secretory and make surfactant?
Type II
What are the factors that determine Diffusion of O2?
Surface area available
Integrity of Alveoli-Capillary Membrane
Amount of Hgb
Diffusion of co-efficient of gas (amount of contact time)
Driving Pressures
What is a normal V:Q Ratio?
Ventilation (V): 4 L/min
Perfusion (Q): 5 L/min
V:Q = 4:5 = 0.8 ratio
***More perfusion than ventilation
What does it mean that a normal V:Q Ratio is 4:5 (0.8)?
not all alveoli are working 100% during each inspiration
***more air is coming in than is passing into the blood
What does a V:Q Ratio of LESS THAN 0.8 indicate?
decrease in ventilation in relation to perfusion
more deoxygenated blood is returning to left heart
What does a V:Q Ratio of MORE THAN 0.8 indicate?
decrease in perfusion in relation to ventilation
- *PE
- *Cardiogenic Shock
Which V:Q Ratio would indicate a likely PE?
greater than 0.8
***oxygen is getting all the way to alveoli, but the blood flow is block at the capillary level
What is PaO2?
Amount of oxygen dissolved in plasma
***Normal value is 3%
What is oxygen that is bound to Hemoglobin called?
SaO2 (Oxygen Saturation)
***Normal value is around 97%)
Oxyhemoglobin Disassociation Curve:
What does the bottom axis measure?
What does the vertical axis measure?
PaO2
SaO2
Oxyhemoglobin Disassociation Curve:
What are factors that will shift the curve left (decreasing SaO2)?
Increase pH
Decrease PCO2
Decrease Temp
Decrease 2, 3-DGP
Carboxyhemoglobin
Hgb Ranier
Hgb Hiroshima
Hgb San Francisco
Oxyhemoglobin Disassociation Curve:
What are factors that will shift the curve right (increasing SaO2)?
Decrease pH
Increase PCO2
Increase Temp
Increase 2, 3-DGP
Hgb Kansas
Hgb Seattle
What is the purpose of the Oxyhemoglobin Disassociation Curve?
describes the ability of Hgb to bind to oxygen at normal arterial O2 tension levels and release it at lower PO2 levels
Oxyhemoglobin Disassociation Curve:
What is the benefit of the UPPER FLAT PORTION?
arterial association which protects the body by enabling Hgb to load O2, despite large decreases in PaO2
ex:
PaO2 is 100 mm Hg yields SaO2 of 98%
PaO2 is 60 mm Hg yields SaO2 of 89%
Oxyhemoglobin Disassociation Curve:
What is the benefit of the LOWER STEEP PORTION?
Venous dissociation portion that protects the body by allowing the tissues to withdraw large amounts of O2
ex:
PaO2 is 50 mm Hg yields SaO2 of 80%
PaO2 is 40 mm Hg yields SaO2 of 70%
Oxyhemoglobin Disassociation Curve:
What is a SHIFT TO THE RIGHT?
Enhances oxygen delivery to tissues
Hgb has LESS affinity for Oxygen, which means it releases it more readily to tissues
R’s
Right shift
Release O2 more Readily
Oxyhemoglobin Disassociation Curve:
What are some causes of the SHIFT TO THE RIGHT?
R’s
- Reduced pH (acidosis)
- hypeRcapnia (PCO2 increase)
- feveR
- incRease levels of 2,3-DPG