T11, Neuroimaging, Functional neuroimaging Flashcards
What happens when a neuron is active?
- More blood flow
- -> more o2 and glucose (even though it consumes 02 and glucose
what technique can we use to image/simulate(?) the electrical and synaptic activity?
Electrophysiology
EEG
MEG
what can be used to image the metabolic response?
FDG-PET
Techniques to measure flow flow?
- FMRI
- NIRS/DOI
- SPECT
- O2-PET
- H20-PET
information about EEG?
- first technique to simulate a brain
- measuring electrical activity fro
- Different types of electrodes:
- -> scalp electrode (EEG) measure potential differences?
- ->
- ->
- implants e.g. epilepsy
- easiness
- cost
- portability
- effect
EEG sources?
- depolarization
- zink
volume conduction in the extracellular space
the postsynaptic potential willl be measured most of the time
Open-fieldcell vs Closed-field cel?
open-field can be In series and added together while closed-field cancel out and no strong current
Does it matter if it is the gyros or the sulcus when measuring with EEG and MEG?
- EEG can always measure
- MEG can only measure in sulcus as the dendroids has to be in a certain direction
Which are the different brain rhythms?
- Gamma
- -> 30-60 Hz
- -> Excited - Beta
- -> 18-21 Hz
- -> Relaxed - Alpha
- -> 9-11 Hz
- -> Drowsy - Theta
- -> 4-7 Hz
- -> Asleep - Delta
- -> 0,5-2 Hz
- -> Deep sleep
what is common for epileptic activity?
spikes and seizures
Source reconstruction problem?
We have the sensors and we have a lot of sources but we don’t know where??
scalp signal is NOT source signals
what is ICA?
?
Forward problem?
going from the source model to the sensors
The inverse problem?
sensors to sources
