T1 - Final Exam: Fincher

Question 1

What is the route of administration for the eye surface?

Answer 1

Ophthalmic

Question 2

What is the route of administration for the epidermal surface?

Answer 2

Trasdermal

Question 3

What is the route of administration for the veins?

Answer 3

Intravenous injection or infusion

Question 4

What is the route of administration for the subcutaneous fat?

Answer 4

Subcutaneous

Question 5

What is the route of administration for between the cheek and gum?

Answer 5

Buccal

Question 6

What is the route of administration for the mouth (inhaled)?

Answer 6

Pulmonary

Question 7

Which of the following are the two most common ways in which we measure drug concentrations in humans?

Answer 7

Urine and Plasma

Question 8

What is pharmaceutics?

Answer 8

Examines the physiochemical properties of drugs and dosage forms as it relates to dosage form design

Question 9

What is biopharmaceutics?

Answer 9

Examines the interrelationship between the physicochemical properties of drugs, the dosage form, and the route of administration on the rate and extent of drug absorption into the body

Question 10

What is pharmacokinetics?

Answer 10

Studies the movement of drugs within the body

Question 11

What is LADME?

Answer 11

Liberation, Absorption, Distribution, Metabolism, Excretion

Question 12

What is the quantitative measurement of drugs?

Answer 12

Blood pressure and cholestrol

Question 13

What is the qualitative measurement of drugs?

Answer 13

Subjective, measure of pain

Question 14

What is bioavailability?

Answer 14

Proportion (percent or fraction) of an administered dose of unchanged drug that reaches the systemic circulation

Question 15

What is clearance?

Answer 15

The volume of plasma cleared of drug per unit time

Question 16

What is half-life?

Answer 16

The time required for plasma concentration of drug to decrease by 50%.

Question 17

What is volume of distribution?

Answer 17

An indicator of how well distributed a drug is in the body

Question 18

What is liberation?

Answer 18

Release of the drug from its dosage form

Question 19

Where is drug typically absorbed?

Answer 19

Into the bloodstream

Question 20

How are drugs metabolized?

Answer 20

By enzymes

Question 21

How much is the difference between the distribution of intracellular and extracellular?

Answer 21

Intracellular is doubled than extracellular

Question 22

What is Schedule I drug?

Answer 22

Drugs with no accepted medical use, or other substances with a high potential for abuse

Question 23

What are examples of schedule 1 drug?

Answer 23

LSD, mescaline, peyote, methaqualone, marijuana, heroin

Question 24

What is Schedule II?

Answer 24

Drugs with accepted medical uses and a high potential for abuse that if abused may lead to severe psychologic or physical dependence

Question 25

What are examples of Schedule II?

Answer 25

Morphine, cocaine, methamphetamine, amobarbital, and other such drugs

Question 26

What is Schedule III drug?

Answer 26

Drugs with accepted medical uses and a potential for abuse less than those listed in schedules I and II that if abused may lead to moderate psychologic or physical dependence.

Question 27

What is an example of Schedule III?

Answer 27

Codeine, butalbital, testosterone

Question 28

What is a Schedule IV drug?

Answer 28

Drugs with accepted medical uses and low potential for abuse relative to those in schedule III that if abused may lead to limited physical dependence or psychologic dependence relative to drugs in schedule III

Question 29

What is an example of a schedule IV drug?

Answer 29

Difenoxin, diazepam, oxazepam, and similar agents

Question 30

What is a Schedule V drug?

Answer 30

Drugs with accepted medical uses and low potential for abuse relative to those in schedule IV that if abused may lead to limited physical dependence or psychologic dependence relative to drugs in schedule IV

Question 31

What is an example of a Schedule V?

Answer 31

Dihydrocodeine, diphenoxylate, and similar agents

Question 32

What are the components of an NDC number?

Answer 32

1st segment: Drug's manufacturer 2nd segment: Product 3rd segment: Packaging (size and quantity)

Question 33

What is Class I of drug product recall?

Answer 33

There is a reasonable probability that the use of or exposure to a violative product will cause serious adverse health consequences or death.

Question 34

What is Class II of drug product recall?

Answer 34

The use of or exposure to a violative product may cause temporary or medically reversible adverse health consequences or the probability of serious adverse health consequences is remote

Question 35

What is Class III of drug product recall?

Answer 35

The use of or exposure to a violative product is not likely to cause adverse health consequences

Question 36

What is isotonic solution?

Answer 36

A solution having the same osmotic pressure as the specific body fluid

Question 37

What is hypertonic solution?

Answer 37

Solutions of higher osmotic pressure than that of a body fluid causing the cell to shrink or crenate

Question 38

What is a hypotonic solution?

Answer 38

Solutions of lower osmotic pressure than that of a body fluid causing the cell to lysis or swelling

Question 39

What is the behaviors of non electrolytes in a non aqueous solution?

Answer 39

Behaves as a ideal solution

Question 40

What is the behaviors of a strong electrolytes in a non aqueous solution?

Answer 40

Ions pair

Question 41

What is the behaviors of a weak electrolytes in a non aqueous solution?

Answer 41

Behave as a ideal solution

Question 42

What is the behaviors of a weak electrolytes in an aqueous solution?

Answer 42

1. Weak current 2. Partially ionized 3. Colligative properties based on ionization 4. Weak acids, weak bases, benzoic acid, atropine

Question 43

What is the behaviors of a strong electrolytes in an aqueous solution?

Answer 43

1. Conduct strong current 2. Totally ionized 3. Exhibit irregular colligative properties 4. Mineral acids, strong bases, all salts

Question 44

What is the behaviors of non electrolytes in an aqueous solution?

Answer 44

1. Do not conduct current 2. No ions present 3. Exhibit regular colligative properties 4. Sugars, alcohols, acetamide, acetone, glycerin

Question 45

What are the 4 colligative properties?

Answer 45

1. Osmotic Pressure 2. Vapor Pressure Lowering 3. Freezing Point Depression 4. Boiling Point Elevation

Question 46

What is a colligative property?

Answer 46

The physical properties of solutions vary according to the concentration of the dissolved solute

Question 47

What is osmotic pressure?

Answer 47

The pressure created when solvent passes through a semipermeable membrane from a dilute solution into a more concentrated one

Question 48

What is the the osmotic pressure created by a non electrolyte?

Answer 48

Only the concentration affect the pressure

Question 49

What is the the osmotic pressure created by an electrolyte?

Answer 49

Dissolution and concentration affect pressure

Question 50

What is the relationship between solutes and pressure?

Answer 50

Solutes that dissociate have greater number of particles in solution and exert a greater osmotic pressure than undissociated ones

Question 51

Which of the following molecules will exert the largest freezing point depression, non-electrolyte or electrolyte?

Answer 51

Nonelectrolyte

Question 52

What are the primary anions and cations in plasma?

Answer 52

Na+ and Cl-

Question 53

What are the primary anions and cations in ECF?

Answer 53

Na+ and Cl-

Question 54

What are the primary anions and cations in ICF?

Answer 54

K+ and HPO4-

Question 55

What is the ideal body osmolarity?

Answer 55

300 +/-